TONABERSAT
Tonabersat
CAS: 175013-84-0
Molecular Formula: C20H19ClFNO4
TONABERSAT - Names and Identifiers
TONABERSAT - Physico-chemical Properties
| Molecular Formula | C20H19ClFNO4 |
| Molar Mass | 391.82 |
| Density | 1.38 |
| Boling Point | 554.5±50.0 °C(Predicted) |
| Appearance | powder |
| Color | white to beige |
| pKa | 11.86±0.60(Predicted) |
| Storage Condition | 2-8°C |
| In vitro study | Tonabersat, a novel benzopyran derivative, inhibits cortical spreading depression (CSD) and therefore might be able to inhibit the early migraine mechanisms. |
| In vivo study | Treatment with Tonabersat (10 mg/kg) significantly inhibits progression of metastatic lesions. Addition of NSC 241240 to either agent profoundly inhibits brain metastasis. |
TONABERSAT - Risk and Safety
| UN IDs | UN 3077 9 / PGIII |
TONABERSAT - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.552 ml | 12.761 ml | 25.522 ml |
| 5 mM | 0.51 ml | 2.552 ml | 5.104 ml |
| 10 mM | 0.255 ml | 1.276 ml | 2.552 ml |
| 5 mM | 0.051 ml | 0.255 ml | 0.51 ml |
Last Update：2024-01-02 23:10:35
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