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Sulfamonomethioxine

sulfamonomethoxine

CAS: 1220-83-3

Molecular Formula: C11H12N4O3S

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Sulfamonomethioxine - Names and Identifiers

Name sulfamonomethoxine
Synonyms SMM
DS-36
ici32525
sulfamonomethoxine
Sulfamonomethioxine
4-SulfanilaMido-6-MethoxypyriMidine
4-Methoxy-6-sulfanilaMidopyriMidine
6-Methoxy-4-sulfanilaMidopyriMidine
n(sup1)-(6-methoxy-4-pyrimidinyl)-sulfanilamid
4-amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide
4-azanyl-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide
Sulfamonomethoxine,4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide
4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamideN-(6-Methoxy-4-pyrimidinyl)sulfanilamide
CAS 1220-83-3
EINECS 624-483-8
InChI InChI=1/C11H12N4O3S/c1-18-11-6-10(13-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,14,15)

Sulfamonomethioxine - Physico-chemical Properties

Molecular FormulaC11H12N4O3S
Molar Mass280.3
Density1.3936 (rough estimate)
Melting Point203-2060C
Boling Point513℃
Flash Point>110°(230°F)
Water SolubilitySoluble in water at 10mg/ml with warming. Also soluble in ethanol or methanol
Solubility ≤ 3.0% water slightly soluble in water
Vapor Presure1.2E-10mmHg at 25°C
AppearanceWhite to off-white crystalline powder
Colorwhite to white with yellow cast
BRN621128
pKapKa 5.94 (Uncertain)
Storage ConditionKeep in dark place,Inert atmosphere,2-8°C
Refractive Index1.6200 (estimate)
MDLMFCD00063466
Physical and Chemical PropertiesWhite or off-white crystalline powder, odorless, tasteless. Melting Point 204-206 °c. Very slightly soluble in water and ethanol, soluble in dilute acid, dilute alkali. Light is easy to be oxidized and gradually dark.
UseSulfa drugs for hemolytic Streptococcus, Pneumonia cocci and meningococcal infections

Sulfamonomethioxine - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk CodesR36/37/38 - Irritating to eyes, respiratory system and skin.
R43 - May cause sensitization by skin contact
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany2
RTECSWP0550000
HS Code29350090
Hazard ClassIRRITANT
ToxicityLD50 oral in rabbit: > 10gm/kg

Sulfamonomethioxine - Upstream Downstream Industry

Raw MaterialsEthyl malonate
Trichloroethylene

Sulfamonomethioxine - Reference

Reference
Show more
1. [IF=4.098] Tancong Liao et al."Multi-spectroscopic and molecular docking studies of human serum albumin interactions with sulfametoxydiazine and sulfamonomethoxine."Spectrochim Acta A. 2021 Feb;246:119000

Sulfamonomethioxine - Chemical properties

Open Data Unverified Data

white or off-white crystalline powder, odorless and tasteless. Melting Point 204-206 °c. Very slightly soluble in water and ethanol, soluble in dilute acid, dilute alkali. Light is easy to be oxidized and gradually dark.

Last Update:2024-01-02 23:10:35

Sulfamonomethioxine - Production method

Open Data Unverified Data

prepared from dibutyl malonate by cyclization, condensation, etherification, acidification and other steps.

Last Update:2022-01-01 08:49:19

Sulfamonomethioxine - Safety Information

Open Data Unverified Data

mark of dangerous goods Xi
Hazard code 36/37/38-43
Safety instructions 26-36
WGK Germany 2
Rpecs#: WP0550000
HazardClass IRRITANT

Last Update:2022-01-01 08:49:20
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View History
Sulfamonomethioxine
22601-29-2
acifolic
氢氧化镍(II), N
酸性红142
324054-99-1
WIN552122
氯化铁
3-hydroxy-acrylic acid ethyl ester
AZD8186
Raw Materials for Sulfamonomethioxine
Ethyl malonate
Trichloroethylene
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