SCM-PEG-AA,SCM-PEG-COOH - Names and Identifiers
SCM-PEG-AA,SCM-PEG-COOH - Physico-chemical Properties
SCM-PEG-AA,SCM-PEG-COOH - Introduction
SCM-PEG-AA, SCM-PEG-COOH(SCM-PEG-AA, SCM-PEG-COOH) is a polymer compound. It consists of a carboxyl group on a polyethylene glycol (PEG) backbone and an N-hydroxysuccinimide ester (SCM) group.
The polymer has the following properties:
1. Solubility: SCM-PEG-AA, SCM-PEG-COOH has good solubility in water, convenient in vivo application.
2. Biocompatibility: Polyethylene glycol is a material with high biocompatibility. SCM-PEG-AA, SCM-PEG-COOH also has good biocompatibility and can reduce biological toxicity.
3. can be modified: by modifying the carboxyl group and SCM group on the PEG chain, the characteristics of the polymer can be changed, such as adjusting its solubility, hydrophilicity, realizing directional guidance and controlling the sustained release properties of the drug.
In the fields of medicine and biology, SCM-PEG-AA, SCM-PEG-COOH can be used as drug carriers or basic materials of drug delivery systems. Specific applications include:
1. Construction of drug sustained release system: SCMP-PEG-AA, SCM-PEG-COOH has the property of drug sustained release and can be used as a carrier of drugs to realize the controlled release of drugs.
2. modification of proteins, peptides and low molecular drugs: through modification SCM-PEG-AA, SCM-PEG-COOH, molecules such as drugs or proteins can be linked to PEG chains, which can improve the stability of drugs and improve the pharmacokinetic properties of drugs.
3. Cell imaging: SCM-PEG-AA, SCM-PEG-COOH has good biocompatibility and can be used for cell labeling and imaging applications.
the preparation SCM-PEG-AA, the SCM-PEG-COOH method is to first react SCM with carboxyl-containing PEG to obtain PEG esterified product with SCM group, and then undergo hydrolysis reaction to generate SCM-PEG-AA and SCM-PEG-COOH.
Regarding safety information, SCM-PEG-AA, the SCM-PEG-COOH has no obvious toxicity or sensitization under general use conditions. However, the specific use and operation should be determined according to the specific situation and experimental conditions, and the laboratory safety operation specification should be followed. When using or disposing of these compounds, care should be taken to prevent contact with the skin, eyes, and mouth, and to avoid inhalation or ingestion. Strengthen ventilation and follow proper laboratory procedures to ensure personal and environmental safety.
Last Update:2024-04-09 20:45:29