Rituxan
Rituximab
CAS: 174722-31-7
Molecular Formula: C6416H9874N1688O1987S44
Rituxan - Names and Identifiers
Rituxan - Physico-chemical Properties
| Molecular Formula | C6416H9874N1688O1987S44 |
| Storage Condition | -20℃，避光 |
| In vitro study | The potency of Rituximab depends primarily on its complement-dependent toxicity (CDC), complement-dependent cytotoxicity (CDCC), antibody-dependent cytotoxicity (ADCC), and apoptosis-inducing effects. Rituximab induces the death of malignant B cells in vitro. The potency of the action varies with different target cells. In vitro, the cellular changes induced by Rituximab are: p38 MAPK, NF-κB, ERK1/2, inhibition of AKT anti-apoptotic, survival signaling pathways. Rituximab is highly effective in mediating complement-dependent toxicity (CMC) of different B cell lines and malignant B cells. The CD20 binding capacity of Rituximab was concentration-dependent. |
| In vivo study | Some in vivo tumor models have demonstrated that the anti-tumor activity of rituximab depends (at least in part) on complement. Rituximab can deplete B cells for several months and thus can be an effective regimen for the treatment of B cell-mediated autoimmune diseases. Rituximab is widely used in the treatment of hematological tumors and is currently in the development of drugs for the treatment of several autoimmune diseases. |
Supplier List
Featured ProductsSpot supply
Product Name: Rituximab Visit Supplier Webpage Request for quotationCAS: 174722-31-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Rituximab Request for quotationCAS: 174722-31-7
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Rituximab Visit Supplier Webpage Request for quotationCAS: 174722-31-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Rituximab Visit Supplier Webpage Request for quotationCAS: 174722-31-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Featured ProductsSpot supply
Product Name: Rituximab Visit Supplier Webpage Request for quotationCAS: 174722-31-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Rituximab Request for quotationCAS: 174722-31-7
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Rituximab Visit Supplier Webpage Request for quotationCAS: 174722-31-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Rituximab Visit Supplier Webpage Request for quotationCAS: 174722-31-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
View History