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RIT-X

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane

CAS: 144164-11-4

Molecular Formula: C23H27N3O3S

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RIT-X - Names and Identifiers

Name (2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane
Synonyms RIT-X
RT-10
Ritonavir Impurity 1
(5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamic acid
thiazol-5-ylmethyl (2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-ylcarbamate
Thiazol-5-ylMethyl ((2S,3S,5S)-5-aMino-3-hydroxy-1,6-diphenylhexan-2-yl)carbaMate
1,3-thiazol-5-ylmethyl [(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate
1,3-Thiazol-5-ylMethyl N-[(1S,2S,4S)-4-aMino-1-benzyl-2-hydroxy-5-phenylpentyl]carbaMate
(2S,3S,5S)-5-amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane
2S,3S,5S-5-AMINO-2-[N-[[(5-THIAZOLYL)METHOXY]CARBONYL]AMINO]-1,6-DIPHENYL-3-HYDROXYHEXANE
(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane
Carbamic acid,N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-,5-thiazolylmethyl ester
CAS 144164-11-4
InChI InChI=1/C23H27N3O3S/c24-19(11-17-7-3-1-4-8-17)13-22(27)21(12-18-9-5-2-6-10-18)26-23(28)29-15-20-14-25-16-30-20/h1-10,14,16,19,21-22,27H,11-13,15,24H2,(H,26,28)/t19-,21-,22-/m0/s1

RIT-X - Physico-chemical Properties

Molecular FormulaC23H27N3O3S
Molar Mass425.54
Density1.251±0.06 g/cm3(Predicted)
Boling Point656.1±55.0 °C(Predicted)
Flash Point350.6°C
Vapor Presure4.17E-18mmHg at 25°C
Appearancepale yellow oily
pKa11.48±0.46(Predicted)
Storage Conditionunder inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index1.619

RIT-X - Introduction

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1, also known as thiazole hexane dibenzyloxycarbonyl proline (Fmoc). The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid
-Molecular formula: C32H32N4O4S
-Molecular weight: 576.68g/mol
-Melting Point: 198-202 ° C
-Solubility: Soluble in organic solvents such as methanol, dichloromethane and ethanol, slightly soluble in water

Use:
- Fmoc proline is a commonly used Amine protecting group, which is widely used in the synthesis and modification of peptides in solid phase synthesis.
-It can react with amino acid residues by forming imides, and deprotect when needed, so that the peptide chain remains intact during the synthesis process.
- Fmoc proline is also used in peptide chemistry research, drug discovery, and biomedical applications.

Method:
(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1, calcium can be obtained by synthesis. Specific laws include:
1. Chemical synthesis using related compounds.
2. The structure of the product was confirmed by mass spectrometry.

Safety Information:
Fmoc Proline has low toxicity under normal operating conditions, but the following safety precautions still need to be paid attention:
-Avoid inhalation or skin contact. Wear protective gloves and face mask.
-Maintain well-ventilated laboratory conditions during operation.
-For accidental contact, rinse immediately with plenty of water and seek medical advice.
-Keep dry during storage and avoid contact with oxidants and strong acids.
Last Update:2024-04-09 02:00:42
RIT-X
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Shanghai Macklin Biochemical Co., Ltd
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: (2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Visit Supplier Webpage Request for quotation
CAS: 144164-11-4
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate Visit Supplier Webpage Request for quotation
CAS: 144164-11-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate Request for quotation
CAS: 144164-11-4
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate Visit Supplier Webpage Request for quotation
CAS: 144164-11-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Ritonavir Intermediate Visit Supplier Webpage Request for quotation
CAS: 144164-11-4
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: (2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Visit Supplier Webpage Request for quotation
CAS: 144164-11-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
RIT-X
SEC-BUTANOL
CCI 5537
61-33-6
1287-13-4
28048-33-1
1435-52-5
6240-44-4
131-54-4
17329-20-3
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