R-MP
R-(-)-2-Methylpiperazine
CAS: 75336-86-6
Molecular Formula: C5H12N2
R-MP - Names and Identifiers
R-MP - Physico-chemical Properties
| Molecular Formula | C5H12N2 |
| Molar Mass | 100.16 |
| Density | 0.9305 (estimate) |
| Melting Point | 86-93℃ |
| Boling Point | 155-156℃ |
| Specific Rotation(α) | -18 º (c=1, toluene) |
| Flash Point | 65℃ |
| Water Solubility | soluble |
| Appearance | Crystalline Powder, Crystals and/or Chunks |
| Color | White to yellow |
| BRN | 3647994 |
| pKa | 9.31±0.40(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Sensitive | Air Sensitive & Hygroscopic |
| Refractive Index | 1.4378 (estimate) |
| Physical and Chemical Properties | melting point 91-93°C(lit.) boiling point 155 specific rotation -18 ° (c = 1, toluene) flash point 149 °F Storage Conditions flagmables area water solubility soluble sensitivity Air Sensitive & hygropic BRN 3647994 |
| Use | New chiral groups are widely used in the synthesis of chiral drugs. |
R-MP - Risk and Safety
| Hazard Symbols | F - Flammable C - Corrosive  |
| Risk Codes | R11 - Highly Flammable R34 - Causes burns |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 1325 |
| WGK Germany | 2 |
| HS Code | 29335990 |
| Hazard Class | 4.1 |
| Packing Group | III |
R-MP - Introduction
R-(-)-2-Methylpiperazine is an organic compound whose chemical formula is C5H12N2. It is a colorless to slightly yellow liquid with a peculiar pungent odor. R-(-)-2-Methylpiperazine is chiral, and R-(-) enantiomer is its common optical isomer.
R-(-)-2-Methylpiperazine has several application areas. It is commonly used as a pharmaceutical intermediate and can be used in the synthesis of antidepressant and anxiolytic drugs. In addition, it can also be used for pesticide synthesis.
There are many methods for preparing R-(-)-2-Methylpiperazine. The common method is to react 2-methyl piperazine with a chiral reducing agent (such as D-glycine). The reaction is usually carried out under an inert atmosphere to avoid the influence of water and oxygen.
For safety information, R-(-)-2-Methylpiperazine needs to be stored in a cool, dry and well-ventilated place. It is an irritant substance and contact with the skin, eyes and respiratory tract may cause irritation and discomfort. Appropriate protective measures, such as wearing chemical protective gloves, protective glasses and breathing apparatus, are required during handling and storage. If you come into contact with the substance, rinse immediately with plenty of water and seek medical help.
R-(-)-2-Methylpiperazine has several application areas. It is commonly used as a pharmaceutical intermediate and can be used in the synthesis of antidepressant and anxiolytic drugs. In addition, it can also be used for pesticide synthesis.
There are many methods for preparing R-(-)-2-Methylpiperazine. The common method is to react 2-methyl piperazine with a chiral reducing agent (such as D-glycine). The reaction is usually carried out under an inert atmosphere to avoid the influence of water and oxygen.
For safety information, R-(-)-2-Methylpiperazine needs to be stored in a cool, dry and well-ventilated place. It is an irritant substance and contact with the skin, eyes and respiratory tract may cause irritation and discomfort. Appropriate protective measures, such as wearing chemical protective gloves, protective glasses and breathing apparatus, are required during handling and storage. If you come into contact with the substance, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 20:52:54
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