PI-3065
PI-3065
CAS: 955977-50-1
Molecular Formula: C27H31FN6OS
PI-3065 - Names and Identifiers
PI-3065 - Physico-chemical Properties
| Molecular Formula | C27H31FN6OS |
| Molar Mass | 506.64 |
| Density | 1.372±0.06 g/cm3(Predicted) |
| Solubility | DMSO |
| pKa | 14.80±0.30(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| In vitro study | PI-3065 shows no inhibition on the growth of 4T1 cells, which do not expressing detectable levels of p110δ. |
| In vivo study | In mouse model, PI-3065 (75 mg/kg, p.o.) also suppresses 4T1 tumor growth and metastasis via inactivation of p110δ. In the LSL.KrasG12D/+; p53R172H/+; PdxCretg/+ (or KPC) model of pancreatic ductal adenocarcinoma, PI-3065 prolongs survival and reduces the incidence of macroscopic metastases and other disease-associated pathologies. |
PI-3065 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.974 ml | 9.869 ml | 19.738 ml |
| 5 mM | 0.395 ml | 1.974 ml | 3.948 ml |
| 10 mM | 0.197 ml | 0.987 ml | 1.974 ml |
| 5 mM | 0.039 ml | 0.197 ml | 0.395 ml |
Last Update：2024-01-02 23:10:35
PI-3065 - Introduction
PI-3065 is an organic compound with the chemical name 2,5-bis (9,9-dimethyl)-9-(2-acryloyloxyethyl) phenylthiourea. The following is a description of the nature, use, preparation and safety information of PI-3065:
Nature:
- PI-3065 is a colorless or light yellow powdery solid.
-It has good stability at room temperature.
- PI-3065 is insoluble in water, but soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol.
Use:
- PI-3065 is a selective TLR8 (Toll-like receptor 8) agonist that mimics the response of the immune system.
-It can be used to study immune regulation, anti-inflammatory and anti-tumor fields.
Preparation Method:
- PI-3065 can be prepared by chemical synthesis, but the specific preparation method may be a trade secret, so I cannot provide specific steps.
Safety Information:
- PI-3065 is generally safe under normal use conditions, but protective measures are still required.
-Since PI-3065 has not been widely used in clinical or pharmaceutical applications, its toxicity and side effects require further study and evaluation.
-When using PI-3065, it is recommended to follow appropriate laboratory practices and safe operating methods.
Nature:
- PI-3065 is a colorless or light yellow powdery solid.
-It has good stability at room temperature.
- PI-3065 is insoluble in water, but soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol.
Use:
- PI-3065 is a selective TLR8 (Toll-like receptor 8) agonist that mimics the response of the immune system.
-It can be used to study immune regulation, anti-inflammatory and anti-tumor fields.
Preparation Method:
- PI-3065 can be prepared by chemical synthesis, but the specific preparation method may be a trade secret, so I cannot provide specific steps.
Safety Information:
- PI-3065 is generally safe under normal use conditions, but protective measures are still required.
-Since PI-3065 has not been widely used in clinical or pharmaceutical applications, its toxicity and side effects require further study and evaluation.
-When using PI-3065, it is recommended to follow appropriate laboratory practices and safe operating methods.
Last Update：2024-04-09 15:16:34
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Featured ProductsSpot supply
Product Name: PI-3065 Visit Supplier Webpage Request for quotationCAS: 955977-50-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: PI-3065 Request for quotationCAS: 955977-50-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: PI-3065 Visit Supplier Webpage Request for quotationCAS: 955977-50-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: PI-3065 Visit Supplier Webpage Request for quotationCAS: 955977-50-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: PI-3065 Visit Supplier Webpage Request for quotationCAS: 955977-50-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
PI-3065
Dimethylhydroquinone Ether
H-VAL-OBZL TOS
red lead oxide
(2-PHENYLETHYL)TRICHLOROSILANE
ACT 128800
Dimethylhydroquinone Ether
H-VAL-OBZL TOS
red lead oxide
(2-PHENYLETHYL)TRICHLOROSILANE
ACT 128800