Molecular Formula | C23H25F4N3O3S |
Molar Mass | 499.52 |
Density | 1.371±0.06 g/cm3(Predicted) |
Boling Point | 642.7±65.0 °C(Predicted) |
Solubility | 10 mM in DMSO |
pKa | 8.95±0.20(Predicted) |
Storage Condition | -20℃ |
In vitro study | The inhibitory activity of (R)-PFI-2 against human SETD7 was 500-fold higher than that of its isomer,(S)-PFI-2. In the cellular environment, through direct interaction with SETD7, it affects the localization of Yes-related protein and the deletion of phenotypic Setd7 gene in the Hippo pathway signal. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.002 ml | 10.01 ml | 20.019 ml |
5 mM | 0.4 ml | 2.002 ml | 4.004 ml |
10 mM | 0.2 ml | 1.001 ml | 2.002 ml |
5 mM | 0.04 ml | 0.2 ml | 0.4 ml |