Name | Methyl 3-oxopentanoate |
Synonyms | PEM MOP Methy3-oxo-valerate Methyl 3-oxovalerate methyl3-0xopentanoate Methyl,1,3-oxovalerate Methyl 3-oxopentanoate METHYL PROPIONYLACETATE methyl-3-oxo pentanoate Methyl 3-oxo-n-valerate Methyl 3-oxo-pentanoate Methyl beta-ketovalerate methyl propionyl acetate PROPIONYLACETIC ACID METHYL ESTER Valeric acid, 3-oxo-, methyl ester |
CAS | 30414-53-0 |
EINECS | 250-184-3 |
InChI | InChI=1/C6H10O3/c1-3-5(7)4-6(8)9-2/h3-4H2,1-2H3 |
InChIKey | XJMIXEAZMCTAGH-UHFFFAOYSA-N |
Molecular Formula | C6H10O3 |
Molar Mass | 130.14 |
Density | 1.037g/mLat 25°C(lit.) |
Melting Point | -35 °C |
Boling Point | 73-74°C5mm Hg(lit.) |
Flash Point | 71 °C |
Water Solubility | SLIGHTLY SOLUBLE |
Solubility | Chloroform |
Vapor Presure | 0.221mmHg at 25°C |
Appearance | Liquid |
Specific Gravity | 1.05 |
Color | Clear colorless to slightly yellow |
BRN | 1753684 |
pKa | 10.56±0.46(Predicted) |
Storage Condition | Store below +30°C. |
Refractive Index | n20/D 1.422(lit.) |
Physical and Chemical Properties | Melting Point:-35 Boiling Point: 95 - 97 at 48mm Hg density: 1.039 flash point: 71 |
Use | Used as a pharmaceutical Intermediate |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
HS Code | 29183000 |
Hazard Note | Flammable |
Hazard Class | IRRITANT |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
Overview | Methyl propionyl acetate, also known as methyl 3-oxo valerate, belongs to β-keto esters and is an important organic synthesis intermediate for many drugs. |
Preparation | Methyl propionyl acetate can be prepared from methyl bromoacetate and propionitrile in one step. |
use | as a pharmaceutical intermediate |