Nilutamide
Nilutamide
CAS: 63612-50-0
Molecular Formula: C12H10F3N3O4
Nilutamide - Names and Identifiers
Nilutamide - Physico-chemical Properties
| Molecular Formula | C12H10F3N3O4 |
| Molar Mass | 317.22 |
| Density | 1.463±0.06 g/cm3(Predicted) |
| Melting Point | 1490C |
| Appearance | morphological solid |
| pKa | 7.59±0.70(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Physical and Chemical Properties | Chemical properties crystallize from ethanol, melting point 149 ℃. Acute toxic LD50 male mice, male rats (mg/kg):215,195 oral; 180,135 intraperitoneal injection. |
| Use | Use non-steroidal anti-androgen, but no effect on other steroid receptors. For metastatic prostate cancer. |
Nilutamide - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R60 - May impair fertility R25 - Toxic if swallowed |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | NI9453300 |
| HS Code | 2933210000 |
Nilutamide - Upstream Downstream Industry
| Raw Materials | Isopropylamine Phenyl isocyanate Dimethyl sulfoxide COPPER(II) OXIDE Diphenyl ether 5,5-Diphenylhydantoin |
Nilutamide - Nature
| Solubility | Very slightly soluble in water, freely soluble in acetone, soluble in anhydrous ethanol. |
Last Update：2024-04-10 22:29:15
Nilutamide - Uses and synthesis methods
biological activity
Nilutamide (RU23908) is a non-steroidal anti-androgen drug with affinity for androgen receptors. For the treatment of prostate cancer.
Target
Target Value
Androgen Receptor
Production method
49.6g 3-trifluoromethyl-4-nitrophenyl isocyanate reacts with 18g α-cyano isopropylamine to obtain 27g compound (Ⅰ). Then acidic hydrolysis to obtain Nilutamide.
Last Update：2024-04-09 21:31:49
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Featured ProductsSpot supply
Product Name: RU23908 Visit Supplier Webpage Request for quotationCAS: 63612-50-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Nilutamide Request for quotationCAS: 63612-50-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Nilutamide Visit Supplier Webpage Request for quotationCAS: 63612-50-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Nilutamide Visit Supplier Webpage Request for quotationCAS: 63612-50-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Nilutamide Visit Supplier Webpage Request for quotationCAS: 63612-50-0
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Spot supply
Product Name: Nilutamide? Visit Supplier Webpage Request for quotationCAS: 63612-50-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Multiple Specifications
Product Name: Nilutamide Visit Supplier Webpage Request for quotationCAS: 63612-50-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
Nilutamide
Tolbutamide (200 mg)
antimony
ms551
Silicate(2-),hexafluoro-,dipotassium
496775-95-2
Magesium Chloride
C.I. 76535
avibest
Tolbutamide (200 mg)
antimony
ms551
Silicate(2-),hexafluoro-,dipotassium
496775-95-2
Magesium Chloride
C.I. 76535
avibest
Raw Materials for Nilutamide
Isopropylamine
Phenyl isocyanate
Dimethyl sulfoxide
COPPER(II) OXIDE
Diphenyl ether
5,5-Diphenylhydantoin
Phenyl isocyanate
Dimethyl sulfoxide
COPPER(II) OXIDE
Diphenyl ether
5,5-Diphenylhydantoin