Neoandrographolide
Neoandrographolide
CAS: 27215-14-1
Molecular Formula: C26H40O8
Neoandrographolide - Names and Identifiers
Neoandrographolide - Physico-chemical Properties
| Molecular Formula | C26H40O8 |
| Molar Mass | 480.59 |
| Density | 1.27±0.1 g/cm3(Predicted) |
| Melting Point | 167～168℃ |
| Boling Point | 668.1±55.0 °C(Predicted) |
| Specific Rotation(α) | -48°(pyridine) |
| Flash Point | 220.092°C |
| Solubility | Soluble in methanol, ethanol, acetone, pyridine, slightly soluble in chloroform, water, insoluble in ether, petroleum ether. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Colorless columnar crystal |
| Color | White |
| pKa | 12.93±0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.576 |
| MDL | MFCD07779130 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Andrographis paniculata. |
Neoandrographolide - Risk and Safety
| WGK Germany | 3 |
Neoandrographolide - Reference
| Reference Show more | 1. Zhou, rushun, Jiangyan. Improvement of quality standard for veterinary Andrographis paniculata injection [J]. Chinese Journal of Veterinary Medicine 2020 v.39;No.221(02):59-62. 2. Masai Yan, Xie Shutong, Song powder cloud. Chemical constituents of ganmaoqing tablets and identification of its metabolites in rats [J]. Journal of Shenyang Pharmaceutical University, 2020,37(07):624-637. 3. Zhou Rusun, Jiang Yan, Chen Qiyou, etc. Study on ultrasonic extraction technology of Andrographis paniculata [J]. Chinese Journal of Veterinary Medicine, 2019, 053(008):66-70. 4. Zhang Shixin, Peng Litao, Fan Ming, et al. Screening of active compounds inhibiting Penicillium cinerea of postharvest pear fruit from clinical medicine [J]. Food science 2020 41(5). 5. Shao Yanhua, Wang Jiangang, Lai Xiaoping, etc. Study on HPLC fingerprint of diterpene Lactones from Andrographis paniculata [J]. Chinese herbal medicine, 2014, 37(2):219-223. 6. Zeng Wu Jing, Xu Ling, He Qiu Ling, etc. Agronomic traits of Andrographis paniculata and their correlation with diterpene lactones [J]. Chinese Journal of Traditional Chinese Medicine, 2019, 26 (15). 7. [IF = 6.17] Lu Qi et al."The inhibition of colorectal cancer growth by the natural product macrocarpal I." Free radial Bio Med. 2021 Jan;162:383 |
Neoandrographolide - Reference Information
| effect | neoandrographolide has the effect of inhibiting and delaying the temperature rise caused by pneumococcus and hemolytic streptococcus B, and also has the effect of relieving cough and asthma. Suitable for acute bacillary dysentery, acute gastroenteritis, upper respiratory tract infection, acute almond inflammation. Studies have shown that neoandrographolide has a positive effect on the prevention and control of heatstroke. |
| Biological activity | Neoandrographolide (Neoandrographolide) is a diterpenoid isolated from Andrographis paniculata compound. |
| chemical properties | white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Andrographis paniculata. |
| use | andrographis paniculata new glycoside has the effects of removing heat and detoxification, diminishing inflammation and relieving pain. used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: clearing away heat and detoxification, reducing swelling and relieving pain. |
Last Update：2024-04-09 20:52:54
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