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Nalpha-FMOC-L-Tryptophan

N(alpha)-Fmoc-L-tryptophan

CAS: 35737-15-6

Molecular Formula: C26H22N2O4

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Nalpha-FMOC-L-Tryptophan - Names and Identifiers

Name N(alpha)-Fmoc-L-tryptophan
Synonyms Fmoc-Trp-OH
Fmoc-L-tryptophan
Nalpha-Fmoc-L-Tryptophan
N-ALPHA-FMOC-L-TRYPTOPHAN
N(alpha)-Fmoc-L-tryptophan
N-(9-FLUORENYLMETHOXYCARBONYL)-L-TRYPTOPHAN
N-9-FLUORENYLMETHYLOXYCARBONYL-L-TRYPTOPHAN
N-[(9H-fluoren-9-ylmethoxy)carbonyl]tryptophan
N(alpha)-9-Fluorenylmethoxycarbonyl-L-tryptophan
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-tryptophan
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-TRYPTOPHAN
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tryptophan
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-TRYPTOPHAN
NALPHA-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-TRYPTOPHAN
(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(1H-indol-3-yl)propanoate
CAS 35737-15-6
EINECS 252-706-5
InChI InChI=1/C26H22N2O4/c29-25(30)24(13-16-14-27-23-12-6-5-7-17(16)23)28-26(31)32-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,14,22,24,27H,13,15H2,(H,28,31)(H,29,30)/p-1/t24-/m0/s1
InChIKey MGHMWKZOLAAOTD-DEOSSOPVSA-N

Nalpha-FMOC-L-Tryptophan - Physico-chemical Properties

Molecular FormulaC26H22N2O4
Molar Mass426.46
Density1.2501 (rough estimate)
Melting Point182-185°C(lit.)
Boling Point541.92°C (rough estimate)
Specific Rotation(α)-29 º (c=1,DMF)
Flash Point384.3°C
Solubility almost transparency in Pyridine
Vapor Presure2.87E-21mmHg at 25°C
AppearanceWhite powder
ColorWhite to Almost white
BRN4216624
pKa3.89±0.10(Predicted)
Storage Condition2-8°C
Refractive Index-28.5 ° (C=1, DMF)
MDLMFCD00037126
UseUsed for biochemical reagents, peptide synthesis.

Nalpha-FMOC-L-Tryptophan - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S27 - Take off immediately all contaminated clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany3
HS Code2933 99 80

Nalpha-FMOC-L-Tryptophan - Reference Information

use Fmoc-L-tryptophan is L-tryptophan protected by Fmo and can be used as an intermediate in pharmaceutical synthesis.
Cyclic peptide compounds can be used as tachykinin antagonists, and can be prepared by Fmoc-protected D-and L-tryptophan compounds.
Synthesis For Fmoc peptide synthesis, trifluoroacetic acid (TFA) is usually used as a high-concentration (90-95%) deprotectant, and the remaining 5-10% It is usually water and various scavengers, especially sulfur-containing compounds, such as thioanisole and 1, 2-ethanedithiol. The scavenger is used to inhibit the side reaction of reactive cations produced by TFA with sensitive amino acid side chains such as Trp under the action of protective groups.
Last Update:2024-04-10 22:29:15
Nalpha-FMOC-L-Tryptophan
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Fmoc-Trp-OH Visit Supplier Webpage Request for quotation
CAS: 35737-15-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
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Product Name: Fmoc-Trp-OH Request for quotation
CAS: 35737-15-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: Fmoc-Trp-OH Visit Supplier Webpage Request for quotation
CAS: 35737-15-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
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SKYRUN INDUSTRIAL CO.,LTD
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Product Name: Nalpha-FMOC-L-Tryptophan Visit Supplier Webpage Request for quotation
CAS: 35737-15-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Fmoc-Trp-OH Visit Supplier Webpage Request for quotation
CAS: 35737-15-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
Nalpha-FMOC-L-Tryptophan
708-53-2
BUMETRIZOLE
MOLYBDENUM TRISULFIDE
Sulfur
307-79-9
PHENOL (2,6-13C2)
β-Naphthoflavone
m-Anisic acid
Cilazapril
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