NOTOGINSENOSIDE-FE
Notoginseng triterpenes
CAS: 88105-29-7
Molecular Formula: C47H80O17
NOTOGINSENOSIDE-FE - Names and Identifiers
NOTOGINSENOSIDE-FE - Physico-chemical Properties
| Molecular Formula | C47H80O17 |
| Molar Mass | 917.14 |
| Density | 1.36±0.1 g/cm3(Predicted) |
| Melting Point | 179-184°C |
| Boling Point | 994.1±65.0 °C(Predicted) |
| Specific Rotation(α) | (c, 0.8 in MeOH)-0.3 |
| Solubility | Soluble in methanol, DMSO, insoluble in chloroform |
| Appearance | White powder |
| pKa | 12.91±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| Sensitive | Easily absorbing moisture |
| MDL | MFCD11111354 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from panoginseng flowers. |
NOTOGINSENOSIDE-FE - Reference
| Reference Show more | 1. Jingjing Liu, Chunyu Jiang, Xu Ma, Jianbo Wang, Notoginsenoside Fc attenuates high glucose-induced vascular endothelial cell injury via upregulation of PPAR-γ in diabetic Sprague–Dawley rats, Vascular Pharmacology, Volume 109, 2018, Pages 27-35, ISSN 1537- 2. [IF=2.629] Zhang Meiyu et al."In Vitro Transformation of Protopanaxadiol Saponins in Human Intestinal Flora and Its Effect on Intestinal Flora."Evid-Based Compl Alt. 2021;2021:1735803 |
NOTOGINSENOSIDE-FE - Introduction
Notoginseng triterpenes is an active ingredient extracted from the stems and leaves of Panax Notoginseng. It is a natural diterpenoid with a chemical structure of diterpene ketones. Notoginseng triterpenes has a variety of pharmacological activities, including antioxidant, anti-inflammatory, anti-platelet aggregation, improving cardiac and cerebral circulation.
The main use of Notoginseng triterpenes is health care and medicinal. It is commonly used in the treatment of cardiovascular diseases and cerebrovascular diseases, and has the effects of improving microcirculation, reducing blood lipids, resisting thrombosis and enhancing immunity. In addition, it can also be used in skin anti-aging products, which has the effect of anti-oxidation and promoting collagen production.
Notoginseng triterpenes is generally obtained from the roots and leaves of Panax Notoginseng by supercritical fluid extraction, solvent extraction, enzymatic hydrolysis and other methods. Among them, supercritical fluid extraction is an environmentally friendly and efficient extraction method.
Regarding the safety information of Notoginseng triterpenes, within the general dose range, the safety of Notoginseng triterpenes is better. However, individual tolerance to Notoginseng triterpenes may vary, and long-term high-dose use may cause some adverse reactions, such as gastrointestinal discomfort, dizziness, palpitation, etc. Therefore, before using Notoginseng triterpenes, it is recommended to consult the advice of a professional doctor or pharmacist and use it in accordance with the recommend dose. For pregnant women, lactating women, children and people with specific diseases, it should be used with caution or avoided.
The main use of Notoginseng triterpenes is health care and medicinal. It is commonly used in the treatment of cardiovascular diseases and cerebrovascular diseases, and has the effects of improving microcirculation, reducing blood lipids, resisting thrombosis and enhancing immunity. In addition, it can also be used in skin anti-aging products, which has the effect of anti-oxidation and promoting collagen production.
Notoginseng triterpenes is generally obtained from the roots and leaves of Panax Notoginseng by supercritical fluid extraction, solvent extraction, enzymatic hydrolysis and other methods. Among them, supercritical fluid extraction is an environmentally friendly and efficient extraction method.
Regarding the safety information of Notoginseng triterpenes, within the general dose range, the safety of Notoginseng triterpenes is better. However, individual tolerance to Notoginseng triterpenes may vary, and long-term high-dose use may cause some adverse reactions, such as gastrointestinal discomfort, dizziness, palpitation, etc. Therefore, before using Notoginseng triterpenes, it is recommended to consult the advice of a professional doctor or pharmacist and use it in accordance with the recommend dose. For pregnant women, lactating women, children and people with specific diseases, it should be used with caution or avoided.
Last Update：2024-04-09 21:54:55
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