N,N-DIETHYL-2-PHENYLACETAMIDE
N,N-DIETHYL-2-PHENYLACETAMIDE
CAS: 2431-96-1
Molecular Formula: C12H17NO
N,N-DIETHYL-2-PHENYLACETAMIDE - Names and Identifiers
N,N-DIETHYL-2-PHENYLACETAMIDE - Physico-chemical Properties
| Molecular Formula | C12H17NO |
| Molar Mass | 191.27 |
| Density | 1.004 g/mL at 25 °C(lit.) |
| Melting Point | 84-86 °C |
| Boling Point | 169-171 °C18 mm Hg(lit.) |
| Flash Point | >230 °F |
| pKa | -0.44±0.70(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | n20/D 1.522(lit.) |
N,N-DIETHYL-2-PHENYLACETAMIDE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | 36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | AB7410000 |
| Toxicity | LD50 in guinea pigs, rats, rabbits, mice (g/kg): 7, 3-4, 3.5, ~2 dermally (Rao, 1991) |
N,N-DIETHYL-2-PHENYLACETAMIDE - Upstream Downstream Industry
| Raw Materials | benzyl(chloro)zinc Benzene, (2-bromo-2-nitroethyl)- Benzylmalononitrile Phenylbromoethyne N-BENZYLDIETHYLAMINE Phenylacetyl chloride Methyl phenylacetate Benzyl chloride Diethylamine |
N,N-DIETHYL-2-PHENYLACETAMIDE - Introduction
N,N-DIETHYL-2-PHENYLACETAMIDE is an organic compound with the chemical formula C12H17NO. The following is a description of its nature, use, preparation and safety information:
Nature:
N,N-DIETHYL-2-PHENYLACETAMIDE is a colorless to pale yellow liquid. It has low volatility at room temperature and is soluble in most organic solvents such as alcohols, ethers and aromatic hydrocarbons. It has a molecular weight of 203.3g/mol.
Use:
N,N-DIETHYL-2-PHENYLACETAMIDE are often used as intermediates in biological and pharmaceutical fields. It can be used as a reagent in the synthesis of drugs, but also can be used in organic synthesis of N-substitution reaction and the reduction of carboxylic acid derivatives and other reactions.
Method:
N,N-DIETHYL-2-PHENYLACETAMIDE can be prepared by the reaction of phenylacetyl chloride (C6H5CH2COCl) with diethylamine ((C2H5)2NH). During the reaction, diethylamine is added dropwise to phenylacetyl chloride to react to form N,N-DIETHYL-2-PHENYLACETAMIDE with evolution of hydrogen chloride gas. The target product was finally purified by distillation.
Safety Information:
N,N-DIETHYL-2-PHENYLACETAMIDE has low toxicity, but still need to pay attention to safe operation. It should be stored in a cool, dry place, away from fire and oxidizing agents. Wear appropriate personal protective equipment such as goggles and gloves during use. If you are in contact with skin or eyes, rinse immediately with plenty of water and seek medical examination.
Please note that when handling and using chemical substances, correct operating procedures should be followed, and relevant safety information and appropriate disposal methods should be understood.
Nature:
N,N-DIETHYL-2-PHENYLACETAMIDE is a colorless to pale yellow liquid. It has low volatility at room temperature and is soluble in most organic solvents such as alcohols, ethers and aromatic hydrocarbons. It has a molecular weight of 203.3g/mol.
Use:
N,N-DIETHYL-2-PHENYLACETAMIDE are often used as intermediates in biological and pharmaceutical fields. It can be used as a reagent in the synthesis of drugs, but also can be used in organic synthesis of N-substitution reaction and the reduction of carboxylic acid derivatives and other reactions.
Method:
N,N-DIETHYL-2-PHENYLACETAMIDE can be prepared by the reaction of phenylacetyl chloride (C6H5CH2COCl) with diethylamine ((C2H5)2NH). During the reaction, diethylamine is added dropwise to phenylacetyl chloride to react to form N,N-DIETHYL-2-PHENYLACETAMIDE with evolution of hydrogen chloride gas. The target product was finally purified by distillation.
Safety Information:
N,N-DIETHYL-2-PHENYLACETAMIDE has low toxicity, but still need to pay attention to safe operation. It should be stored in a cool, dry place, away from fire and oxidizing agents. Wear appropriate personal protective equipment such as goggles and gloves during use. If you are in contact with skin or eyes, rinse immediately with plenty of water and seek medical examination.
Please note that when handling and using chemical substances, correct operating procedures should be followed, and relevant safety information and appropriate disposal methods should be understood.
Last Update：2024-04-09 15:18:02
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View History
N,N-DIETHYL-2-PHENYLACETAMIDE
Vitamin B
161803-04-9
Tricresyl phosphate
(-)-CAMPHORQUINONE
86209-51-0
Trimethylphenylammonium
401636-59-7
83194-71-1
颜料黄 3
Vitamin B
161803-04-9
Tricresyl phosphate
(-)-CAMPHORQUINONE
86209-51-0
Trimethylphenylammonium
401636-59-7
83194-71-1
颜料黄 3
Raw Materials for N,N-DIETHYL-2-PHENYLACETAMIDE
benzyl(chloro)zinc
Benzene, (2-bromo-2-nitroethyl)-
Benzylmalononitrile
N-BENZYLDIETHYLAMINE
Phenylacetyl chloride
Methyl phenylacetate
Benzene, (2-bromo-2-nitroethyl)-
Benzylmalononitrile
N-BENZYLDIETHYLAMINE
Phenylacetyl chloride
Methyl phenylacetate