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Lemborexant

Lemborexant

CAS: 1369764-02-2

Molecular Formula: C22H20F2N4O2

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Lemborexant - Names and Identifiers

Name Lemborexant
Synonyms Lemborexant
E-2006 Lemborexant
(1R,2S)-2-[[(2,4-Dimethyl-5-pyrimidinyl)oxy]methyl]-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)cyclopropanecarboxamide
2-((1S,2S)-2-(((2,4-dimethylpyrimidin-5-yl)oxy)methyl)-2-(3-fluorophenyl)cyclopropyl)-N-(5-fluoropyridin-2-yl)acetamide
CAS 1369764-02-2

Lemborexant - Physico-chemical Properties

Molecular FormulaC22H20F2N4O2
Molar Mass410.4166
Density1.347±0.06 g/cm3(Predicted)
Melting Point173 - 175°C
Boling Point596.1±50.0 °C(Predicted)
Solubility DMSO: ≥ 30 mg/mL
AppearanceForm Solid, color White to Off-White
pKa12.30±0.40(Predicted)
Storage Condition-20°C, Inert atmosphere
UseThe lemborexant of use is a dual inhibitor of OX1 and OX2 receptors, discovered and developed by Eisai. The compound inhibits orexin by competitively binding to 2 subtypes of orexin receptors (orexin receptor 1 and receptor 2).

Lemborexant - Preparation solution concentration reference

 1mg5mg10mg
1 mM2.437 ml12.183 ml24.365 ml
5 mM0.487 ml2.437 ml4.873 ml
10 mM0.244 ml1.218 ml2.437 ml
5 mM0.049 ml0.244 ml0.487 ml
Last Update:2024-01-02 23:10:35

Lemborexant - Nature

solubility DMSO (Slightly), Methanol (Slightly)
Last Update:2024-04-10 22:29:15

Lemborexant - Application

lemborexant interfere with orexin neurotransmission and purposeful promotion of sleep initiation and maintenance. At present, Aisai is cooperating with Purdue to develop lemborexant for the treatment of various sleep disorders.

Last Update:2024-04-10 22:29:15
Lemborexant
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Shanghai Amole Biotechnology Co., Ltd.
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CAS: 1369764-02-2
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CAS: 1369764-02-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Lemborexant Request for quotation
CAS: 1369764-02-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Lemborexant Visit Supplier Webpage Request for quotation
CAS: 1369764-02-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Lemborexant Visit Supplier Webpage Request for quotation
CAS: 1369764-02-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
Lemborexant
Acetochlor 100 μg/mL in Methanol
FENCHOL
CYSTAMINE SULFATE
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