Isoprene
Isoprene
CAS: 78-79-5
Molecular Formula: C5H8
Isoprene - Names and Identifiers
| Name | Isoprene |
| Synonyms | Isoprene ACETATE BUFFER SODIUM ACETATE BUFFER 2-METHYL-1,3-HEXADIENE 2-Methyl-1,3-butadiene 2-METHYL-1,3-BUTADIENE ACETATE BUFFER, PH 4.5 2-METHYL-BUTA-1,3-DIENE SODIUM ACETATE ACETIC ACID SODIUM ACETATE ACETIC ACID BUFFER |
| CAS | 78-79-5 |
| EINECS | 201-143-3 |
| InChI | InChI=1/C5H8/c1-4-5(2)3/h4H,1-2H2,3H3 |
Isoprene - Physico-chemical Properties
| Molecular Formula | C5H8 |
| Molar Mass | 68.12 |
| Density | 0.681g/mLat 25°C(lit.) |
| Melting Point | 323-329°C(lit.) |
| Boling Point | 34°C(lit.) |
| Flash Point | −65°F |
| Water Solubility | 0.07 g/100 mL |
| Solubility | 0.7g/l |
| Vapor Presure | 8.82 psi ( 20 °C) |
| Vapor Density | 2.35 (vs air) |
| Appearance | solid |
| Color | Clear colorless to very pale yellow |
| Odor | petroleum-like odor |
| Maximum wavelength(λmax) | ['231nm(neat)(lit.)'] |
| Merck | 14,5201 |
| BRN | 969158 |
| pKa | >14 (Schwarzenbach et al., 1993) |
| Storage Condition | Store at <= 20°C. |
| Stability | Stability Extremely flammable. Readily forms explosive mixtures with air. Note low flash point, low boiling point, high vapour pressure. Unstable - prone to spontaneous polymerization. |
| Explosive Limit | 1-9.7%(V) |
| Refractive Index | n20/D 1.422(lit.) |
| Physical and Chemical Properties | Colorless volatile, irritating oily liquid. boiling point 34.07 ℃ freezing point -145.96 ℃ relative density 0.681 refractive index 1.4219 flash point -48 ℃ solubility insoluble in water, soluble in benzene, soluble in ethanol, ether, acetone. |
| Use | Mainly used for the production of properties close to natural rubber Polyisoprene Rubber, butyl rubber and SIS thermoplastic elastomer second monomer |
Isoprene - Risk and Safety
| Risk Codes | R45 - May cause cancer R12 - Extremely Flammable R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R68 - Possible risk of irreversible effects R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition. |
| UN IDs | UN 1218 3/PG 1 |
| WGK Germany | 1 |
| RTECS | NT4037000 |
| TSCA | Yes |
| HS Code | 2901 24 00 |
| Hazard Class | 3 |
| Packing Group | I |
| Toxicity | LD50 for mice: 144 mg isoprene vapors/l air (Gostinskii) |
Isoprene - Upstream Downstream Industry
| Downstream Products | 1-Chloro-3-methyl-2-butene 6-Methyl-5-hepten-2-one |
Isoprene - Nature
Open Data Verified Data
colorless volatile, irritating oily liquid. Freezing point -145. 96 °c. Boiling point 34. 07 °c. Flash point -48 °c. Spontaneous ignition point 220. Insoluble in water, soluble in benzene, soluble in ethanol, ether, acetone. Form an explosive mixture with air with an explosion limit of> 1.6%.
Last Update：2025-06-10 22:55:16
Isoprene - Preparation Method
Open Data Verified Data
- dehydrogenation method: isopentane is dehydrogenated to give isopentene, isopentene is re-dehydrogenated to give isoprene, and then the isoprene pure product is separated by acetonitrile or N,N-methyl formamide extractive distillation.
- synthesis method:(1) propylene dimerization method (2) isobutylene formaldehyde method (3) acetylene acetone method
- The C5 fraction, a by-product of the ethylene plant, separates isoprene, and the yield of the C5 fraction is generally 5-8%(wt) of the cracking raw material, wherein the isoprene content is 15%-25%. The yield of isoprene was 0.5%-1.0% of the raw material for pyrolysis. It is difficult to obtain high-purity products by ordinary distillation, generally using extractive distillation and azeotropic distillation, has been industrialized extractive distillation method of acetonitrile, N,N-dimethylformamide, N-methyl pyrrolidone method, etc.
Last Update：2022-01-01 10:13:40
Isoprene - Application
Open Data Verified Data
mainly used in the production of Polyisoprene Rubber, butyl rubber is the second monomer, also used in the manufacture of pesticides, pharmaceuticals, spices and adhesives.
Last Update：2025-08-19 16:24:40
Isoprene - Safety
Open Data Verified Data
- vapors and liquids can irritate the eye, skin, and respiratory system. High concentration of steam has anesthetic effect, oral administration will damage the internal organs, the maximum allowable concentration in the air is 0. 04mg/L. The workplace should be well ventilated and the operator should wear a mask.
- the container shall be filled in a metal barrel, and the container shall be protected from breakage. Preferably stored outdoors or in a flammable warehouse. Due to the conjugated double bond in the molecule, polymerization is easy to occur, and 0. 05% ~ 06% of the polymerization inhibitor is often added in storage. Samples were taken weekly for analysis to verify polymerization inhibitor and polymer content.
Last Update：2025-06-10 22:55:16
Isoprene - Reference Information
| olfactory Threshold | 0.048ppm |
| freezing point | -145.96 ℃ |
| Henry's Law Constant | (x 10-2 atm?m3/mol):3.45 at 18 °C (dynamic stripping cell-MS, Karl et al., 2003) |
| LogP | 2.42 at 20℃ |
| (IARC) carcinogen classification | 2B (Vol. 60, 71) 1999 |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Application | This product is an important monomer of synthetic rubber, and its dosage accounts for 95% of the total output of isoprene, it is mainly used for synthetic isoprene rubber, and its output is only inferior to styrene butadiene rubber and cis butadiene rubber and ranks third in synthetic rubber. Secondly, it is used as a comonomer of synthetic butyl rubber to improve the vulcanization performance of butyl rubber, but the amount is very small. Isoprene is also used in synthetic resin, liquid polyisoprene rubber and so on. Also used in the manufacture of pesticides, pharmaceuticals, spices and adhesives. It is mainly used for Polyisoprene Rubber whose production performance is close to that of natural rubber, and is also the second monomer of butyl rubber and SIS thermoplastic elastomer. The important monomer of synthetic rubber, which accounts for 95% of the total output of isoprene, mainly used in the synthesis of isoprene rubber, the output is second only to styrene butadiene rubber, cis-butadiene rubber. It is also used as a comonomer in the synthesis of butyl rubber to improve the vulcanization properties of butyl rubber. For synthetic resins, liquid polyisoprene rubber. In recent years, it is also used in the synthesis of linanol, squalene and the like, which are intermediates for the further synthesis of spices, drugs, pesticides and the like, and the proportion of the amount is small. |
| production method | isoprene is an important component of the C5 fraction. The C5 fraction mainly comes from the dehydrogenation of isopentane and the dehydrogenation of isopentene obtained from the catalytic cracking of gasoline in the refinery, and the by-products of the cracking of various petroleum feedstocks to ethylene. The C5 fraction has a boiling point of 27.9-49.3 °c. The composition of C5 fraction is complex, and it is difficult to obtain isoprene product with high purity by direct distillation. Extraction distillation and azeotropic distillation are usually used to separate high purity isoprene from cracking C5 fraction. The industrial extractive distillation solvents include acetonitrile, dimethylformamide and N-methylpyrrolidone. In addition to the separation of the C5 fraction of isoprene, industrial production is also used in the synthesis method. For example, it is synthesized from organic raw materials such as propylene, isobutylene, formaldehyde, acetone and acetylene, and can also be obtained from the dehydrogenation of isopentane and isopentene in the C5 fraction. |
| category | flammable liquid |
| toxicity grade | low toxicity |
| Acute toxicity | inhalation-rat LC50:180g/m3/4 H; Inhalation-mouse LC50:139g/m3/2 h |
| explosive hazard characteristics | explosive when mixed with air |
| flammability hazard characteristics | in case of open flame, high temperature, flammable oxidant; Combustion stimulus smoke |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; Stored separately from oxidants and acids |
| extinguishing agent | dry powder, dry sand, carbon dioxide, foam |
| Occupational Standard | TWA 100 mg/m3 |
| spontaneous combustion temperature | 428 ° F. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-10 22:29:15
Supplier List
Featured ProductsSpot supply
Product Name: 2-methyl-1,3-butadiene Request for quotationCAS: 78-79-5
Tel:
Email: 2159287631@qq.com
Mobile: 18369984383（微信同号）
QQ: 2159287631
Spot supply
Product Name: Isoprene Request for quotationCAS: 78-79-5
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Product Name: Isoprene Request for quotation
CAS: 78-79-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 78-79-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Isoprene Request for quotationCAS: 78-79-5
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: Isoprene Request for quotationCAS: 78-79-5
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: Isoprene Visit Supplier Webpage Request for quotationCAS: 78-79-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Isoprene Visit Supplier Webpage Request for quotationCAS: 78-79-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Isoprene Visit Supplier Webpage Request for quotationCAS: 78-79-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: Isoprene Request for quotation
CAS: 78-79-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 78-79-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Product Name: Isoprene Request for quotation
CAS: 78-79-5
Tel:
Email: 94214714@qq.com
Mobile: 13953333566
QQ: 94214714
Send QQ message
CAS: 78-79-5
Tel:
Email: 94214714@qq.com
Mobile: 13953333566
QQ: 94214714
Featured ProductsSpot supply
Product Name: 2-methyl-1,3-butadiene Request for quotationCAS: 78-79-5
Tel:
Email: 2159287631@qq.com
Mobile: 18369984383（微信同号）
QQ: 2159287631
Spot supply
Product Name: Isoprene Request for quotationCAS: 78-79-5
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Product Name: Isoprene Request for quotation
CAS: 78-79-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 78-79-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Isoprene Request for quotationCAS: 78-79-5
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: Isoprene Request for quotationCAS: 78-79-5
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: Isoprene Visit Supplier Webpage Request for quotationCAS: 78-79-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Isoprene Visit Supplier Webpage Request for quotationCAS: 78-79-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Isoprene Visit Supplier Webpage Request for quotationCAS: 78-79-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: Isoprene Request for quotation
CAS: 78-79-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 78-79-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Product Name: Isoprene Request for quotation
CAS: 78-79-5
Tel:
Email: 94214714@qq.com
Mobile: 13953333566
QQ: 94214714Send QQ message
CAS: 78-79-5
Tel:
Email: 94214714@qq.com
Mobile: 13953333566
QQ: 94214714
View History
Downstream Products for Isoprene