Imipenem
Imipenem
CAS: 64221-86-9
Molecular Formula: C12H17N3O4S
Imipenem - Names and Identifiers
Imipenem - Physico-chemical Properties
| Molecular Formula | C12H17N3O4S |
| Molar Mass | 299.35 |
| Density | 1.62±0.1 g/cm3(Predicted) |
| Melting Point | 106-111 C |
| Boling Point | 530.2±60.0 °C(Predicted) |
| Flash Point | 296.9°C |
| Solubility | Sparingly soluble in water, slightly soluble in methanol. |
| Vapor Presure | 3.11E-15mmHg at 25°C |
| pKa | 4.29±0.40(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | 1.721 |
| MDL | MFCD09753321 |
Imipenem - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| HS Code | 29419000 |
Imipenem - Reference
| Reference Show more | 1. He Wenxiu, Lu Enhao, Sha Xianyi. Stability evaluation of different infusion ratios of imipenem cilastatin sodium for injection [J]. Chinese Pharmacoeconomics, 202015 Vol. 7, 60-66 pages, 2020. 2. Wu Lingling, Wei Dun can, Chen Hao Hao. Effect of berberine hydrochloride combined with imipenem on in vitro antibacterial activity of carbapenem-resistant Pseudomonas aeruginosa [J]. China medical science, 2018,8(17):69-72. 3. Shi Qingxin, Lu Xiaoping, Yu Qingfeng, Yang Yang. In vitro drug sensitivity test of carbapenem-resistant Pseudomonas aeruginosa induced by berberine hydrochloride combined with imipenem [J]. Modern doctor of China, 2017,55(01):114-117. 4. Jia Cheng et al. [IF = 4.034]. "Antimicrobial resistance profiles of 5 common bovine mstitis pathogens in large Chinese dairy herds." J Dairy Sci. Mar 2019; 102:2416 5. [IF = 14.919] Qing Guangchao et al."Thermo-responsive triple-function nanotransporter for efficient chemo-photothermal therapy of multidrug-resistant bacterial infection. Nat Commun. 2019 Sep;10(1):1-12 6. [IF=3.743] Guorong Zhang et al."Treatment with andrographolide sulfonate provides additional benefits to imipenem in a mouse model of Klebsiella pneumoniae pneumonia."Biomed Pharmacother. 2019 Sep;117:109065 |
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View History
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