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GSK6853

GSK6853

CAS: 1910124-24-1

Molecular Formula: C22H27N5O3

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GSK6853 - Names and Identifiers

Name GSK6853
Synonyms GSK6853
CS-2243
GSK-6853
GSK 6853
FQWDVNSBYDXPIO-CQSZACIVSA-N
BRPF1 bromodomain inhibitor GS6853
N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxybenzamide
Benzamide, N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxy-
CAS 1910124-24-1

GSK6853 - Physico-chemical Properties

Molecular FormulaC22H27N5O3
Molar Mass409.48
Density1.247±0.06 g/cm3(Predicted)
Boling Point545.9±50.0 °C(Predicted)
Solubility DMSO: ≥ 29 mg/mL
Appearancesolid
ColorWhite
pKa13.03±0.20(Predicted)
Storage ConditionSealed in dry,Store in freezer, under -20°C
StabilityStable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
In vivo study The ip route of administration would be suitable for dosing GSK6853 in potential PK/PD models.

GSK6853 - Preparation solution concentration reference

 1mg5mg10mg
1 mM2.442 ml12.211 ml24.421 ml
5 mM0.488 ml2.442 ml4.884 ml
10 mM0.244 ml1.221 ml2.442 ml
5 mM0.049 ml0.244 ml0.488 ml
Last Update:2024-01-02 23:10:35

GSK6853 - Reference Information

Use GSK6853 can be used in biological studies for preparing bromodomain and PHD finger-containing protein inhibitors.
biological activity GSK6853 is a strong and selective inhibitor of RPF1 acetyllysine (pKd = 9.5), its selectivity is 1600 times that of other acetyl lysine.
in vivo study The ip route of administration would be recommended for dozing GSK6853 in potential PK/PD models.
Last Update:2024-04-10 22:29:15
GSK6853
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Hubei Rhema Reference Materials Technology Co., Ltd.
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CAS: 1910124-24-1
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Shanghai Yuanye Bio-Technology Co., Ltd.
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CAS: 1910124-24-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Hubei Rhema Reference Materials Technology Co., Ltd.
Spot supply
Product Name: GSK6853 Request for quotation
CAS: 1910124-24-1
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249 Click to send a QQ message
Wechat: 15787876101
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: GSK6853 Request for quotation
CAS: 1910124-24-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: GSK6853 Visit Supplier Webpage Request for quotation
CAS: 1910124-24-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: GSK6853 (Standard) Visit Supplier Webpage Request for quotation
CAS: 1910124-24-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: GSK6853 Visit Supplier Webpage Request for quotation
CAS: 1910124-24-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: GSK6853 Visit Supplier Webpage Request for quotation
CAS: 1910124-24-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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