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GS441525

GS-441524

CAS: 1191237-69-0

Molecular Formula: C12H13N5O4

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GS441525 - Names and Identifiers

Name GS-441524
Synonyms GS441525
GS-441524
2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-Altrononitrile
D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-
(2R,3R,4S,5R)-2-(4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLANE-2-
2-C-(4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-2,5-ANHYDRO-3,4-O-(1-METHYLETHYLIDENE)-D-ALTRONONITRI
(2R,3R,4S,5R)-2-(4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)TETRAHYDRO
(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile
(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS 1191237-69-0
EINECS 200-001-8

GS441525 - Physico-chemical Properties

Molecular FormulaC12H13N5O4
Molar Mass291.26
Density1.84±0.1 g/cm3(Predicted)
Melting Point> 233° C (dec.)
Solubility Dissolved in DMSO
AppearanceForm solid, color Off-white
ColorOff-white
pKa12.13±0.70(Predicted)
Storage Condition-20°C
StabilityStable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
UseUse GS-441524 is a small molecule, a competitive inhibitor of nucleoside triphosphate, which shows strong antiviral activity against many RNA viruses. It can inhibit the replication of several different types of RNA viruses, such as severe acute respiratory syndrome (SARS) coronavirus, Middle East respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus and respiratory syncytial virus, etc., and has low cytotoxicity in a wide range of cell lines.

GS441525 - Upstream Downstream Industry

Downstream ProductsRemdesivir N-2

GS441525 - Preparation solution concentration reference

 1mg5mg10mg
1 mM3.433 ml17.167 ml34.334 ml
5 mM0.687 ml3.433 ml6.867 ml
10 mM0.343 ml1.717 ml3.433 ml
5 mM0.069 ml0.343 ml0.687 ml
Last Update:2024-01-02 23:10:35

GS441525 - Nature

Solubility Soluble in DMSO (>25 mg/ml)
Last Update:2024-04-09 01:59:50
GS441525
Supplier List
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: (2R,3R,4S,5R)-2-(4-aminopyrrolo[1,2-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile(GS-441524) Visit Supplier Webpage Request for quotation
CAS: 1191237-69-0
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Shanghai Amole Biotechnology Co., Ltd.
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Product Name: (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile Request for quotation
CAS: 1191237-69-0
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile Visit Supplier Webpage Request for quotation
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MedChemExpress (MCE)
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BOC Sciences
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: GS-441524 Visit Supplier Webpage Request for quotation
CAS: 1191237-69-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: (2R,3R,4S,5R)-2-(4-aminopyrrolo[1,2-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile(GS-441524) Visit Supplier Webpage Request for quotation
CAS: 1191237-69-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile Request for quotation
CAS: 1191237-69-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile Visit Supplier Webpage Request for quotation
CAS: 1191237-69-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Spot supply
Product Name: GS-441524 Visit Supplier Webpage Request for quotation
CAS: 1191237-69-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
BOC Sciences
Spot supply
Product Name: GS-441524 Visit Supplier Webpage Request for quotation
CAS: 1191237-69-0
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: GS-441524 Visit Supplier Webpage Request for quotation
CAS: 1191237-69-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
GS441525
TBE Buffer
4-PYRIMIDINECARBOXYLIC ACID
Downstream Products for GS441525
Remdesivir N-2
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