Fmoc-Lys
Fmoc-Lys-OH
CAS: 105047-45-8
Molecular Formula: C21H24N2O4
Fmoc-Lys - Names and Identifiers
| Name | Fmoc-Lys-OH |
| Synonyms | Fmoc-Lys FMOC-LYS-OH Fmoc-Lys-OH FMOC-L-LYS-OH FMOC-L-LYSINE N-α-Fmoc-L-lysine N-ALPHA-FMOC-L-LYSINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-LYSINE N-alpha-(9-fluorenylmethyloxycarbonyl)-L-lysine N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-LYSINE (2S)-6-ammonio-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}hexanoate (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-6-aminohexanoic acid |
| CAS | 105047-45-8 |
| InChI | InChI=1/C21H24N2O4/c22-12-6-5-11-19(20(24)25)23-21(26)27-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13,22H2,(H,23,26)(H,24,25)/t19-/m0/s1 |
Fmoc-Lys - Physico-chemical Properties
| Molecular Formula | C21H24N2O4 |
| Molar Mass | 368.43 |
| Density | 1.245±0.06 g/cm3(Predicted) |
| Melting Point | 26.8 °C |
| Boling Point | 607.6±55.0 °C(Predicted) |
| Flash Point | 321.3°C |
| Vapor Presure | 1.29E-15mmHg at 25°C |
| pKa | 3.81±0.21(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.6 |
Fmoc-Lys - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29225090 |
Fmoc-Lys - Introduction
Fmoc-lysine is a protected amino acid which contains a Fmoc (5-hydroxy-9-tassyl) protecting group. It has the following properties:
1. Appearance and morphology: Fmoc-lysine is white crystalline powder.
2. Solubility: Soluble in organic solvents, such as dimethyl sulfoxide (DMSO) or dichloromethane (DCM).
3. Stability: Stable under common chemical treatment conditions.
Fmoc-lysine is mainly used for protecting amino acids in peptide synthesis and solid phase synthesis. Its main uses include:
1. Peptide synthesis: As a protected amino acid, Fmoc-lysine can be used to synthesize peptide chains. It can provide protection during peptide synthesis to prevent non-specific side reactions.
2. solid phase synthesis: In solid phase synthesis, Fmoc-lysine can be used as a key component in the construction of polypeptide chain. It can be used consecutively with other protecting amino acids to build polypeptide chains stepwise.
The method of preparing Fmoc-lysine is generally carried out by chemical synthesis. Specific preparation methods include:
1. Through Fmoc-lysine precursor: First, a precursor compound of Fmoc-lysine is synthesized, and then the Fmoc protecting group is removed using an appropriate method to obtain Fmoc-lysine.
In terms of safety information, Fmoc-lysine is relatively safe under general operating conditions, but the following matters should be noted:
1. Avoid inhalation: Adequate ventilation should be used to avoid inhalation of powder or gas during operation.
2. Avoid contact with skin and eyes: Wear appropriate protective gloves and glasses during operation to prevent contact with skin or eyes.
3. Keep dry: Fmoc-lysine should be stored in a dry container to prevent moisture from causing chemical reactions.
1. Appearance and morphology: Fmoc-lysine is white crystalline powder.
2. Solubility: Soluble in organic solvents, such as dimethyl sulfoxide (DMSO) or dichloromethane (DCM).
3. Stability: Stable under common chemical treatment conditions.
Fmoc-lysine is mainly used for protecting amino acids in peptide synthesis and solid phase synthesis. Its main uses include:
1. Peptide synthesis: As a protected amino acid, Fmoc-lysine can be used to synthesize peptide chains. It can provide protection during peptide synthesis to prevent non-specific side reactions.
2. solid phase synthesis: In solid phase synthesis, Fmoc-lysine can be used as a key component in the construction of polypeptide chain. It can be used consecutively with other protecting amino acids to build polypeptide chains stepwise.
The method of preparing Fmoc-lysine is generally carried out by chemical synthesis. Specific preparation methods include:
1. Through Fmoc-lysine precursor: First, a precursor compound of Fmoc-lysine is synthesized, and then the Fmoc protecting group is removed using an appropriate method to obtain Fmoc-lysine.
In terms of safety information, Fmoc-lysine is relatively safe under general operating conditions, but the following matters should be noted:
1. Avoid inhalation: Adequate ventilation should be used to avoid inhalation of powder or gas during operation.
2. Avoid contact with skin and eyes: Wear appropriate protective gloves and glasses during operation to prevent contact with skin or eyes.
3. Keep dry: Fmoc-lysine should be stored in a dry container to prevent moisture from causing chemical reactions.
Last Update：2024-04-09 20:11:46
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