Fmoc-L-3-Nitrophenylalanine
(S)-N-FMOC-3-Amino-3-(3-nitrophenyl)propanoic acid
CAS: 206060-42-6
Molecular Formula: C24H20N2O6
Fmoc-L-3-Nitrophenylalanine - Names and Identifiers
| Name | (S)-N-FMOC-3-Amino-3-(3-nitrophenyl)propanoic acid |
| Synonyms | Fmoc-L-3-NO2-Phe-OH Fmoc-b-Phe(3-NO2)-OH Fmoc-L-3-Nitrophenylalanine Fmoc-3-Nitro-L-phenylalanine FMoc-L-3-NO2-Phe-OH FMoc-3-Nitro-L-Phenylalanine (S)-N-FMOC-3-Amino-3-(3-nitrophenyl)propanoic acid (S)-N-FMOC-3-AMINO-3-(3-NITROPHENYL) PROPANOIC ACID (S)-N-(9-FLUORENYLMETHOXYCARBONYL)-3-AMINO-(3-NITROPHENYL)PROPIONIC ACID (S)-3-(9-FLUORENYLMETHOXYCARBONYLAMINO)-3-(3-NITRO-PHENYL)-PROPIONIC ACID (S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(3-nitrophenyl)propanoic acid |
| CAS | 206060-42-6 |
| InChI | InChI=1/C24H20N2O6/c27-23(28)22(13-15-6-5-7-16(12-15)26(30)31)25-24(29)32-14-21-19-10-3-1-8-17(19)18-9-2-4-11-20(18)21/h1-12,21-22H,13-14H2,(H,25,29)(H,27,28)/t22-/m0/s1 |
Fmoc-L-3-Nitrophenylalanine - Physico-chemical Properties
| Molecular Formula | C24H20N2O6 |
| Molar Mass | 432.43 |
| Density | 1.3445 (rough estimate) |
| Melting Point | 140 °C |
| Boling Point | 546.11°C (rough estimate) |
| Flash Point | 371.1°C |
| Vapor Presure | 5.4E-20mmHg at 25°C |
| pKa | 3.61±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.6300 (estimate) |
Fmoc-L-3-Nitrophenylalanine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| Hazard Class | IRRITANT |
Fmoc-L-3-Nitrophenylalanine - Introduction
(S)-N-FMOC-3-Amino-3-(3-nitrophenyl)propanoic acid is an organic compound containing nitro and phenylalanine groups in its chemical structure. It is an amino acid derivative in which the Amine protecting group is Fmoc (9-fluorofluorenyl).
(S)-N-FMOC-3-Amino-3-(3-nitrophenyl)propanoic acid is commonly used in peptide synthesis in solid phase synthesis. As a protecting group, it can protect the amino group during the synthesis process. It can be used as an integral part of the activator and the crosslinking reagent. In addition, it can also be used in the field of pharmaceutical research, such as the synthesis and modification of peptide drugs.
The preparation method of (S)-N-FMOC-3-Amino-3-(3-nitrophenyl)propanoic acid is usually synthesized by introducing a nitro group into Fmoc-L-phenylalanine.
Regarding safety information,(S)-N-FMOC-3-Amino-3-(3-nitrophenyl)propanoic acid is a chemical, and it is necessary to pay attention to safety during operation, such as wearing appropriate personal protective equipment (such as gloves and glasses). In addition, it is necessary to avoid contact with the skin, eyes and respiratory tract, and to avoid inhalation or ingestion. In use and storage should pay attention to comply with the relevant safety procedures, and keep it in a dry, well-ventilated place. Dispose of properly after use or disposal and comply with relevant waste disposal regulations.
(S)-N-FMOC-3-Amino-3-(3-nitrophenyl)propanoic acid is commonly used in peptide synthesis in solid phase synthesis. As a protecting group, it can protect the amino group during the synthesis process. It can be used as an integral part of the activator and the crosslinking reagent. In addition, it can also be used in the field of pharmaceutical research, such as the synthesis and modification of peptide drugs.
The preparation method of (S)-N-FMOC-3-Amino-3-(3-nitrophenyl)propanoic acid is usually synthesized by introducing a nitro group into Fmoc-L-phenylalanine.
Regarding safety information,(S)-N-FMOC-3-Amino-3-(3-nitrophenyl)propanoic acid is a chemical, and it is necessary to pay attention to safety during operation, such as wearing appropriate personal protective equipment (such as gloves and glasses). In addition, it is necessary to avoid contact with the skin, eyes and respiratory tract, and to avoid inhalation or ingestion. In use and storage should pay attention to comply with the relevant safety procedures, and keep it in a dry, well-ventilated place. Dispose of properly after use or disposal and comply with relevant waste disposal regulations.
Last Update：2024-04-09 20:52:54
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