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Firstcin

Cefozopran hydrochloride

CAS: 113981-44-5;125905-00-2

Molecular Formula: C19H18ClN9O5S2

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Firstcin - Names and Identifiers

Name Cefozopran hydrochloride
Synonyms Czop
D02233
Firstcin
SCE-2787.HCl
Firstcin (tn)
Cefozopran HCl
Cefozopran hydrochlo
SCE-2787 hydrochloride
Cefozopran hydrochloride
Cefozopran hydrochloride (jp15)
(6R,7R)-7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2(Z)-(methoxyimino)acetamido]-3-(imidazo[1,2-b]pyridazinio-1-ylmethyl)-3-cephem-4-carboxylate hydrochloride
1-{[(6R,7R)-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1H-imidazo[1,2-b]pyridazin-4-ium chloride
(6R,7R)-7-[[(2E)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin-4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chloride
[6R-[6alpha,7beta(Z)]]-1-[[7-[[(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1H-imidazo[1,2-b]pyridazinium chloride
CAS 113981-44-5
125905-00-2
EINECS 1806241-263-5
InChI InChI=1/C19H17N9O5S2.ClH/c1-33-24-11(14-23-19(20)35-25-14)15(29)22-12-16(30)28-13(18(31)32)9(8-34-17(12)28)7-26-5-6-27-10(26)3-2-4-21-27;/h2-6,12,17H,7-8H2,1H3,(H3-,20,22,23,25,29,31,32);1H/b24-11-;/t12-,17-;/m1./s1

Firstcin - Physico-chemical Properties

Molecular FormulaC19H18ClN9O5S2
Molar Mass551.98
Storage Conditionunder inert gas (nitrogen or Argon) at 2-8°C
In vitro study Cefozopran (SCE-2787) is a fourth-generation cephalosporin that has good activity against gram-positive organisms including methicillin-susceptible staphylococci, enterococci, and viridans group streptococci; and against gram-negative organisms including hemophilus influenza. Moreover, cefozopran has comparatively good activity against enterococci and P. aeruginosa , which are refractory to other cephalosporins.
In vivo study Cefozopran (SCE-2787) (5-80 mg/kg; s.c.; twice a day for 5 days; four-week-old ICR male mice) is effective against acute respiratory tract infections caused by Kiebsiella pneumonia DT-S. In the model of chronic respiratory tract infection caused by K. pneumoniae 27, Cefozopran (20-80 mg/kg; s.c.; twice a day for 7 days; five-week-old CBA/J female mice) is as effective as Ceftazidime.
Firstcin
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Cefozopran hydrochloride Visit Supplier Webpage Request for quotation
CAS: 113981-44-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
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Product Name: Cefozopranhydrochloride Request for quotation
CAS: 113981-44-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: Cefozopran hydrochloride Visit Supplier Webpage Request for quotation
CAS: 113981-44-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
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MedChemExpress (MCE)
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CAS: 113981-44-5
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Email: sales@medchemexpress.com
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Mobile: 609-228-6898
BOC Sciences
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SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Cefozopran Hydrochloride Visit Supplier Webpage Request for quotation
CAS: 113981-44-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Cefozopran hydrochloride Visit Supplier Webpage Request for quotation
CAS: 113981-44-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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Firstcin
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