FMOC-D-ASN-OH
Fmoc-D-Asn-OH
CAS: 108321-39-7
Molecular Formula: C19H18N2O5
FMOC-D-ASN-OH - Names and Identifiers
| Name | Fmoc-D-Asn-OH |
| Synonyms | FMOC-D-ASN Fmoc-D-Asn-OH FMOC-D-ASN-OH FMOC-D-ASPARAGINE Fmoc-D-asparagine N-α-Fmoc-D-asparagine N-ALPHA-FMOC-D-ASPARAGINE N-(9-FLUORENYLMETHOXYCARBONYL)-D-ASPARAGINE NALPHA-9-Fluorenylmethoxycarbonyl-D-asparagine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-ASPARAGINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-ASPARAGINE N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-asparagine NALPHA-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-D-ASPARAGINE |
| CAS | 108321-39-7 |
| EINECS | 1533716-785-6 |
| InChI | InChI=1/C19H18N2O5/c20-17(22)9-16(18(23)24)21-19(25)26-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10H2,(H2,20,22)(H,21,25)(H,23,24)/t16-/m1/s1 |
FMOC-D-ASN-OH - Physico-chemical Properties
| Molecular Formula | C19H18N2O5 |
| Molar Mass | 354.36 |
| Density | 1.362±0.06 g/cm3(Predicted) |
| Melting Point | ~185°C (dec.) |
| Boling Point | 678.6±55.0 °C(Predicted) |
| Specific Rotation(α) | 11.9 º (c=1%, DMF) |
| Flash Point | 364.2°C |
| Vapor Presure | 2.43E-19mmHg at 25°C |
| Appearance | Solid |
| Color | White to Almost white |
| BRN | 8510210 |
| pKa | 3.68±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 12 ° (C=1, DMF) |
| MDL | MFCD00062956 |
FMOC-D-ASN-OH - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29242100 |
FMOC-D-ASN-OH - Introduction
Fmoc-D-asparagine is an organic compound, which is composed of Fmoc protecting group, D-asparagine and a certain number of reactants. Its structural formula is: Fmoc-D-asparagine.
Fmoc-D-asparagine is a commonly used amino acid protection reagent, mainly used in the synthesis of peptides and proteins. By protecting the α-amino group in the peptide synthesis reaction, their non-specific reaction can be avoided. In addition, it also has the advantages of helping location synthesis, improving yield, purification and reducing side reactions.
The preparation of Fmoc-D-asparagine is generally obtained by reacting D-asparagine with an Fmoc compound in an organic solvent, reacting and purifying through a series of steps. It should be noted that the preparation process needs to be carried out under an inert atmosphere to avoid reaction with moisture and oxygen in the air.
Regarding safety information, Fmoc-D-asparagine is a chemical and needs to be paid attention to during use and storage. Avoid direct contact with skin and eyes. Wear protective gloves and goggles when using. In addition, it should be operated in a well-ventilated laboratory environment and stored in a dry, dark place, away from heat and flammable materials. In the event of any accident, immediately rinse the affected area with plenty of water and seek medical attention immediately.
Fmoc-D-asparagine is a commonly used amino acid protection reagent, mainly used in the synthesis of peptides and proteins. By protecting the α-amino group in the peptide synthesis reaction, their non-specific reaction can be avoided. In addition, it also has the advantages of helping location synthesis, improving yield, purification and reducing side reactions.
The preparation of Fmoc-D-asparagine is generally obtained by reacting D-asparagine with an Fmoc compound in an organic solvent, reacting and purifying through a series of steps. It should be noted that the preparation process needs to be carried out under an inert atmosphere to avoid reaction with moisture and oxygen in the air.
Regarding safety information, Fmoc-D-asparagine is a chemical and needs to be paid attention to during use and storage. Avoid direct contact with skin and eyes. Wear protective gloves and goggles when using. In addition, it should be operated in a well-ventilated laboratory environment and stored in a dry, dark place, away from heat and flammable materials. In the event of any accident, immediately rinse the affected area with plenty of water and seek medical attention immediately.
Last Update：2024-04-09 20:52:54
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