Etifoxine
Etifoxine
CAS: 21715-46-8
Molecular Formula: C17H17ClN2O
Etifoxine - Names and Identifiers
Etifoxine - Physico-chemical Properties
| Molecular Formula | C17H17ClN2O |
| Molar Mass | 300.78 |
| Density | 1.1716 (rough estimate) |
| Melting Point | 90-92℃ |
| Boling Point | 421.2±55.0 °C(Predicted) |
| Vapor Presure | 0-1Pa at 20-25℃ |
| Appearance | Solid:particulate/powder |
| pKa | 4.89±0.40(Predicted) |
| Storage Condition | -20℃ |
| Refractive Index | 1.5800 (estimate) |
| In vitro study | Etifoxine (EFX), at concentrations ranging from 10 to 300 μM (higher concentrations limited its solubility), produces a dose-dependent increase in the [3H]muscimol binding at equilibrium, to 155±2% of its control value at 300 μM EFX. |
Etifoxine - Risk and Safety
| Toxicity | LD50 orally in mice: 12 g/kg (Hoffmann) |
Etifoxine - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.325 ml | 16.623 ml | 33.247 ml |
| 5 mM | 0.665 ml | 3.325 ml | 6.649 ml |
| 10 mM | 0.332 ml | 1.662 ml | 3.325 ml |
| 5 mM | 0.066 ml | 0.332 ml | 0.665 ml |
Last Update：2024-01-02 23:10:35
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