ENLOPLATIN
ENLOPLATIN
CAS: 111523-41-2
Molecular Formula: C13H22N2O5Pt
ENLOPLATIN - Names and Identifiers
ENLOPLATIN - Physico-chemical Properties
| Molecular Formula | C13H22N2O5Pt |
| Molar Mass | 481.4 |
| Melting Point | 260-263 °C (decomp) |
| Physical and Chemical Properties | Chemical Properties Acute Toxicity LD50 Rats (mg/kg):200 Intravenous Injection. |
| Use | Third generation platinum complexes used in the development of anti-tumor drugs. Its antitumor activity spectrum is wider than that of cisplatin, and the renal toxicity is lower. |
ENLOPLATIN - Upstream Downstream Industry
| Raw Materials | Potassium carbonate Malononitrile Ammonium phosphate dibasic 1,1-Cyclobutanedicarboxylic acid Cyclopropane Tetrahydropyran dipotassium tetrachloroplatinate Platinum dichloride |
ENLOPLATIN - Production method
2,2 '-dichloroethyl ether and malononitrile, using potassium carbonate as the condensing agent, refluxing in acetonitrile solvent to obtain 4, 4-dicyanotetrahydropyran, and then the cyano group Reduced to an amino group, reacted with potassium chloroplatinate, and then condensed with silver cyclobutane -1, 1-dicarboxylate to obtain a product. You can also first react potassium chloroplatinate and dimethyl sulfoxide to obtain bis-dimethyl sulfoxide platinum dichloride, and then react with silver cyclobutane -1, 1-dicarboxylate to obtain (1,1-Cyclobutane-dicarboxylic acid-O,O') bis-dimethyl sulfoxide platinum.
The obtained platinum complex is condensed with 4, 4-diamine methyltetrahydropyran to obtain a product.
Last Update：2024-04-10 22:29:15
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Product Name: Enloplatin Request for quotationCAS: 111523-41-2
Tel: 400-968-2212
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Mobile: 18916960931
QQ: 3623107365
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Product Name: Enloplatin Visit Supplier Webpage Request for quotationCAS: 111523-41-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
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Spot supply
Product Name: Enloplatin Visit Supplier Webpage Request for quotationCAS: 111523-41-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: ENLOPLATIN Visit Supplier Webpage Request for quotationCAS: 111523-41-2
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
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Raw Materials for ENLOPLATIN