DSPE-PEG5000-NH2 - Names and Identifiers
DSPE-PEG5000-NH2 - Physico-chemical Properties
DSPE-PEG5000-NH2 - Introduction
DSPE-PEG5000-NH2(DSPE-PEG5000-NH2) is a phospholipid-polyethylene glycol copolymer. It consists of distearoylphosphatidylethanolamine (DSPE) and polyethylene glycol (PEG)5000 chains linked together with an amino crosslinker.
The compound has the following properties:
1. Soluble in many organic solvents and water.
2. Due to the existence of PEG, it has good biocompatibility and can effectively reduce its clearance and immune response in vivo.
3. It has good structural stability and low toxicity.
DSPE-PEG5000-NH2 has a wide range of applications in the biomedical field:
1. As a drug delivery system, it can wrap the drug and enhance its stability, extend its plasma half-life, and increase the concentration of the drug in the target area.
2. for the construction of nanoparticles, nano micelles and nanoparticles and other nano carriers, for targeted drug delivery, gene delivery and imaging diagnosis.
3. can be used for the preparation of functional discrete clusters and nano materials.
Methods for preparing DSPE-PEG5000-NH2 include:
1. Reaction DSPE and PEG5000, and then attach to the end of PEG through a crosslinking agent (such as hard amino acid).
Regarding safety information, the toxicity of DSPE-PEG5000-NH2 is low. However, during operation, protective gloves and glasses should be worn to avoid contact with eyes, skin and application. At the same time, it should be stored in a cool and dry place, away from fire and combustibles. Before use, please carefully read and follow the safety instructions of the relevant chemicals. If necessary, please consult a professional.
Last Update:2024-04-09 21:11:58