CS-54
[(3S)-6-({2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy]-3-biphenylyl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid
CAS: 1000413-72-8
Molecular Formula: C29H32O7S
CS-54 - Names and Identifiers
CS-54 - Physico-chemical Properties
| Molecular Formula | C29H32O7S |
| Molar Mass | 524.63 |
| Density | 1.252 |
| Melting Point | 123-127°C |
| Boling Point | 739.1±60.0 °C(Predicted) |
| Solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 4.36±0.10(Predicted) |
| Storage Condition | Refrigerator |
CS-54 - Reference Information
| introduction | Fasiglifam (TAK-875) is a selective GPR40 agonist. EC50 is 14 nM in CHO cell line expressing human GPR40, which is 400 times more effective than oleic acid. TAK-875 exhibited potent agonist activity and high binding affinity for human GPR40 receptors with a Ki of 38 nM. The TAK-875 showed a weak affinity for the rat GPR40 receptor with a Ki of 140 nM. TAK-875 showed good selectivity, with little agonistic effect on other members of the FFA receptor family, EC50 >10 μM. |
| application | the latest research shows that TAK-875 is a new drug for the treatment of type 2 diabetes. its effect on improving blood sugar control is similar to glimepiride, but the risk of hypoglycemia is significantly lower than the latter. It is a new oral drug that enhances insulin secretion in a glucose-dependent manner. That is, when the blood sugar level is normal, TAK-875 has no effect on insulin secretion. Therefore, TAK-875 can not only effectively control the rise of blood sugar, but also minimize the risk of hypoglycemia. |
Last Update：2024-04-09 19:55:45
Supplier List
Spot supply
Product Name: Tak-875 Request for quotationCAS: 1000413-72-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Fasiglifam Visit Supplier Webpage Request for quotationCAS: 1000413-72-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: TAK-875 Visit Supplier Webpage Request for quotationCAS: 1000413-72-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: TAK-875 Visit Supplier Webpage Request for quotationCAS: 1000413-72-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: TAK875 Visit Supplier Webpage Request for quotationCAS: 1000413-72-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: TAK-875 Visit Supplier Webpage Request for quotation
CAS: 1000413-72-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1000413-72-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: Tak-875 Request for quotationCAS: 1000413-72-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Fasiglifam Visit Supplier Webpage Request for quotationCAS: 1000413-72-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: TAK-875 Visit Supplier Webpage Request for quotationCAS: 1000413-72-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: TAK-875 Visit Supplier Webpage Request for quotationCAS: 1000413-72-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: TAK875 Visit Supplier Webpage Request for quotationCAS: 1000413-72-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: TAK-875 Visit Supplier Webpage Request for quotation
CAS: 1000413-72-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1000413-72-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History