CS-1606
HA 130
CAS: 1229652-21-4
Molecular Formula: C24H19BFNO5S
CS-1606 - Names and Identifiers
CS-1606 - Physico-chemical Properties
| Molecular Formula | C24H19BFNO5S |
| Molar Mass | 463.29 |
| Storage Condition | 2-8℃ |
| In vitro study | HA130 completely blocks the ability of ATX to promote TEM (transendothelial migration). HA130 at 0.3 μM completely ablates the activity of ATX on TK1 uropod formation. |
| In vivo study | HA130 slows T cell migration across lymph node HEVs. HA130 decreases the "outside HEVs/inside HEVs" ratio by 3-4-fold compared to vehicle-treated animals vehicle. The s.c. administration of HA130 induces marked lymphocyte accumulation within the endothelial cell (EC) and sub-EC layers of HEVs in draining lymph nodes (LNs). |
CS-1606 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.158 ml | 10.792 ml | 21.585 ml |
| 5 mM | 0.432 ml | 2.158 ml | 4.317 ml |
| 10 mM | 0.216 ml | 1.079 ml | 2.158 ml |
| 5 mM | 0.043 ml | 0.216 ml | 0.432 ml |
Last Update：2024-01-02 23:10:35
CS-1606 - Reference Information
| biological activity | HA130 is a selective autotaxin (ATX) inhibitor with IC50 of 28 nM. |
| target | Autotaxin 28 nM (IC 50 ) |
| in vitro study | HA130 completely blocks the ability of ATX to promote TEM (transendothelial migration). HA130 at 0.3 μM completely ablates the activity of ATX on TK1 uropod formation. |
| in vivo study | HA130 slow T cell migration across lymph node HEVs. HA130 decreases the "outside HEVs/inside HEVs" ratio by 3-4-fold compared to vehicle-treated animals vehicle. The s.c. administration of HA130 induces marked lymphocyte accumulation with the endothelial cell (EC) and sub-EC layers of HEVs in draining Lmph nodes (LNs). |
Last Update：2024-04-09 20:52:54
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CAS: 1229652-21-4
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Product Name: HA130 Request for quotationCAS: 1229652-21-4
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QQ: 3623107365
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Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
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Product Name: HA130 Visit Supplier Webpage Request for quotationCAS: 1229652-21-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: HA130 Visit Supplier Webpage Request for quotationCAS: 1229652-21-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: HA 130 Visit Supplier Webpage Request for quotation
CAS: 1229652-21-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1229652-21-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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