CPhos
2-Dicyclohexylphosphino-2',6'-bis(diMethylaMino)-1,1'-biphenyl Cphos
CAS: 1160556-64-8
Molecular Formula: C28H41N2P
CPhos - Names and Identifiers
CPhos - Physico-chemical Properties
| Molecular Formula | C28H41N2P |
| Molar Mass | 436.612 |
| Melting Point | 111-113°C |
| Boling Point | 592.8±50.0 °C(Predicted) |
| Appearance | Shape crystal, color yellow-orange |
| pKa | 5.04±0.28(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
CPhos - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
CPhos - Upstream Downstream Industry
CPhos - Introduction
',6'-bis(diMethylaMino)-1,1 '-biphenyl Cphos (',6 '-bis(diMethylaMino)-1,1'-biphenyl Cphos) is an organic compound, also known as Cphos. It has the following properties:
1. Appearance and physical properties: Cphos is a solid and can form white or yellowish crystals. It is insoluble in water at normal temperature, but readily soluble in organic solvents such as diethyl ether and dimethylformamide.
2. use: Cphos is a chiral phosphine ligand, widely used in organic synthesis of metal catalytic reaction. It can form complexes with platinum, palladium and other transition metals, and used in asymmetric catalytic reactions, such as asymmetric hydrogenation, asymmetric reduction, etc.
3. Preparation method: The preparation of Cphos is usually carried out by a multi-step reaction. A common method is to first synthesize 2-chlorodicyclohexylphosphine and then react it with 2-aminoaniline by a substitution reaction to give 2-dicyclohexylphosphine-2 '6'-diaminobiphenyl. Finally, Cphos was introduced into the reaction system by phosphating reaction.
4. Safety information: Regarding the safety information of Cphos, more detailed laboratory evaluation and research are needed to ensure its safety during use. When using the compound in the laboratory, it should be carried out in strict accordance with the relevant safety procedures and wear appropriate protective equipment.
1. Appearance and physical properties: Cphos is a solid and can form white or yellowish crystals. It is insoluble in water at normal temperature, but readily soluble in organic solvents such as diethyl ether and dimethylformamide.
2. use: Cphos is a chiral phosphine ligand, widely used in organic synthesis of metal catalytic reaction. It can form complexes with platinum, palladium and other transition metals, and used in asymmetric catalytic reactions, such as asymmetric hydrogenation, asymmetric reduction, etc.
3. Preparation method: The preparation of Cphos is usually carried out by a multi-step reaction. A common method is to first synthesize 2-chlorodicyclohexylphosphine and then react it with 2-aminoaniline by a substitution reaction to give 2-dicyclohexylphosphine-2 '6'-diaminobiphenyl. Finally, Cphos was introduced into the reaction system by phosphating reaction.
4. Safety information: Regarding the safety information of Cphos, more detailed laboratory evaluation and research are needed to ensure its safety during use. When using the compound in the laboratory, it should be carried out in strict accordance with the relevant safety procedures and wear appropriate protective equipment.
Last Update：2024-04-09 21:00:56
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Raw Materials for CPhos