COOH-PEG-SH

COOH-PEG-SH - Names and Identifiers

Name	COOH-PEG-SH
Synonyms	COOH-PEG-SH

COOH-PEG-SH - Physico-chemical Properties

Storage Condition

-20℃

COOH-PEG-SH - Introduction

Carboxy polyethylene glycol thiol (COOH-PEG-SH) is a compound having a carboxylic acid and a thiol group. It is a carboxyl polymer with a polyethylene glycol group, wherein the polyethylene glycol is connected to the carboxyl group through an ester bond, and the carboxyl group is connected to the thiol group through a sulfur bond.

The main use of COOH-PEG-SH is as a functional surface modifier in the fields of biomedicine and materials science. Due to the biocompatibility and potential solubility of its polyethylene glycol group, it can be used as a stabilizer, cross-linking agent and a slow-release agent in biomaterials, nanoparticles and drug delivery systems. In addition, it can also be used for the preparation of biosensors, the immobilization of biomarkers and enzymes.

The preparation method of COOH-PEG-SH is mainly through the synthesis of carboxyl polyethylene glycol (COOH-PEG) and the reaction of thiol reagent. First, the COOH-PEG is reacted with a thiolating reagent to produce a COOH-PEG-SH. This reaction is typically carried out under temperature and pH conditions and requires a suitable solvent and catalyst to facilitate the reaction.

The COOH-PEG-SH is relatively safe under proper use and handling. However, it is an irritant substance and contact with the skin, eyes and respiratory system should be avoided. During use, it is recommended to wear appropriate protective equipment, such as gloves and goggles. In addition, COOH-PEG-SH should be kept away from fire and high temperatures to prevent decomposition or dangerous reactions. For more detailed safety information, please refer to the specific safety data sheet.

Last Update：2024-04-09 21:01:54