CH-5428402
9-ethyl-6,6-diMethyl-8-(4-Morpholinopiperidin-1-yl)-11-oxo-5a,6,11,11a-tetrahydro-5H-benzo[b]carbazole-3-carbonitrile hydrochloride
CAS: 1256589-74-8
Molecular Formula: C30H35ClN4O2
CH-5428402 - Names and Identifiers
CH-5428402 - Physico-chemical Properties
| Molecular Formula | C30H35ClN4O2 |
| Molar Mass | 519.0775 |
| Solubility | DMSO: 6 mg/mL (Need ultrasonic or warming) |
| Storage Condition | -20℃ |
| Physical and Chemical Properties | The main properties of aletinib hydrochloride is a highly effective inhibitor of ALK kinase with an IC50 value of 1.9nM and is also sensitive to ALK mutant L1196M. |
| Use | Uses Eratinib hydrochloride is a highly selective and effective anaplastic lymphoma kinase (ALK) inhibitor, which can block drug-resistant gatekeeper mutants and lead to decreased cell growth. It is also an intermediate of alitinib (C183360). Alitinib is a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor, which can block drug-resistant gatekeeper mutants and cause cell growth Slow down. |
CH-5428402 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.926 ml | 9.632 ml | 19.265 ml |
| 5 mM | 0.385 ml | 1.926 ml | 3.853 ml |
| 10 mM | 0.193 ml | 0.963 ml | 1.926 ml |
| 5 mM | 0.039 ml | 0.193 ml | 0.385 ml |
Last Update：2024-01-02 23:10:35
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