CBZ-氨基(二乙氧基膦)乙酸甲酯

CBZ-氨基(二乙氧基膦)乙酸甲酯 - Names and Identifiers

Name	METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE
Synonyms	-2-(diethoxyphosphoryl) METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE methyl {[(benzyloxy)carbonyl]amino}(diethoxyphosphoryl)acetate methyl 2-(benzyloxycarbonylamino)-2-(diethoxyphosphoryl)acetate methyl 2-(benzyloxycarbonylamino)-2-(diethyloxyphosphoryl)acetate ethyl2-(((benzyloxy)carbonyl)amino)-2-(diethoxyphosphoryl)acetate Benzyloxycarbonylamino-(diethoxy-phosphoryl)-acetic acid methyl ester Acetic acid, 2-(diethoxyphosphinyl)-2-[[(phenylMethoxy)carbonyl]aMino]-, Methyl ester
CAS	114684-69-4
InChI	InChI=1/C15H22NO7P/c1-4-22-24(19,23-5-2)13(14(17)20-3)16-15(18)21-11-12-9-7-6-8-10-12/h6-10,13H,4-5,11H2,1-3H3,(H,16,18)

CBZ-氨基(二乙氧基膦)乙酸甲酯 - Physico-chemical Properties

Molecular Formula	C15H22NO7P
Molar Mass	359.31
Density	1.235±0.06 g/cm3(Predicted)
Melting Point	79-81℃
Boling Point	500.6±50.0 °C(Predicted)
Flash Point	256.575°C
Vapor Presure	0mmHg at 25°C
pKa	9.59±0.46(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.501

CBZ-氨基(二乙氧基膦)乙酸甲酯 - Upstream Downstream Industry

Raw Materials

methyl 2-(benzyloxycarbonylamino)-2-methoxyacetate
Acetic acid, 2-chloro-2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester
methyl 2-(benzyloxycarbonylamino)-2-hydroxyacetate
N-Benzoxycarbonyl-a -hydroxyglycine
DIETHYL TRIMETHYLSILYL PHOSPHITE
Benzyl carbamate
Triethyl phosphate
Triethyl phosphite

CBZ-氨基(二乙氧基膦)乙酸甲酯 - Introduction

Cbz-amino-(diethoxyphosphoryl)-acetic acid methyl ester is an organic compound whose chemical formula is C16H23N2O6P. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Cbz-amino-(diethoxyphosphoryl)-acetic acid methyl ester is a white crystalline solid.
-Solubility: It is soluble in organic solvents such as toluene, dimethylformamide (DMF) and chloroform, and insoluble in water.

Use:
- Cbz-amino-(diethoxyphosphoryl)-acetic acid methyl ester is an important reagent for the synthesis of blocked amino compounds. Encapsureis a chemical protection strategy used to protect amino groups from reaction or hydrolysis.
-It is often used in the synthesis of drugs and bioactive molecules.

Method:
- Cbz-amino-(diethoxyphosphoryl)-acetic acid methyl ester can be prepared by reacting Cbz-aminoacetic acid methyl ester with diethoxyphosphoryl chloride (PO(OEt)2Cl).

Safety Information:
- Cbz-amino-(diethoxyphosphoryl)-methyl acetate has limited safety information, so the safety instructions of the chemical laboratory should be strictly followed when operating.
-This compound may cause irritation and injury to the human body. Avoid contact with skin and eyes when contacting, and ensure that the compound is used in a well-ventilated environment.
-If the substance is ingested or inhaled, seek medical help immediately and provide the chemical composition and safety data of the substance.

Last Update：2024-04-09 20:49:11