Boc-PEG-AA,BOC-NH-PEG-COOH - Names and Identifiers
Boc-PEG-AA,BOC-NH-PEG-COOH - Physico-chemical Properties
Boc-PEG-AA,BOC-NH-PEG-COOH - Introduction
Boc-PEG-AA, BOC-NH-PEG-COOH(Boc-PEG-AA, BOC-NH-PEG-COOH) is a polyethylene glycol derivative having a Boc protecting group. Its characteristics are as follows:
1. properties: Boc-PEG-AA,BOC-NH-PEG-COOH is a colorless to yellowish solid, soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), dimethyl formamide (DMF). It has good solubility and adjustable molecular weight.
2. use: Boc-PEG-AA,BOC-NH-PEG-COOH are widely used in biomedical fields. It can be used as a carrier material in drug delivery systems, and its solubility, stability and drug release characteristics can be controlled by changing the degree of polymerization and the presence of carboxyl groups. In addition, it can also be used to prepare nanopharmaceutical systems with micellar structure, polymer probes, biosensors, etc.
3. Preparation method: Boc-PEG-AA, the preparation method of BOC-NH-PEG-COOH is generally synthesized by atom transfer radical polymerization (ATRP) or ester exchange reaction. First, polyethylene glycol and some alternative AA groups (such as methacrylic acid, acrylic acid, etc.) are polymerized to synthesize the polymer, and then the protecting group is introduced by reaction with Boc acid or Boc alcohol.
4. safety information: the use of Boc-PEG-AA,BOC-NH-PEG-COOH, need to pay attention to prevent inhalation, swallowing or skin contact. When operating in the laboratory, personal protective equipment such as protective gloves and goggles should be worn and kept in a dry, ventilated place, away from fire and organic materials. If any discomfort or accident occurs, please seek medical assistance immediately and provide relevant materials to the doctor for reference.
Last Update:2024-04-09 21:01:54