BR-Comp

BR-Comp - Names and Identifiers

Name	3-(2-Bromo-1-oxopropyl)-spiro[2H-1,3-benzoxazine-2,1'-cyclohexan]-4(3H)-one
Synonyms	F-9 (A9) BPSBC BR-Comp Meropenem Intermediates Meropenem intermediates F–9 MeropeneM InterMediates(F-9) F-9(Intermediate Of Meropenem) 3-(2-bromopropanoyl)spiro[1,3-benzoxazine-2,1'-cyclohexan]-4(3H)-one 3-(2-Bromo-1-oxopropyl)-spiro[2H-1,3-benzoxazine-2,1'-cyclohexan]-4(3H)-one (R)-4-Nitrobenzyl 2-diazo-4-((2R,3S)-3-((R)-1-hydroxy-ethyl)-4-oxoazetidin-2-yl)-3-oxopentanoa (R)-4-Nitrobenzyl 2-diazo-4-((2R,3S)-3-((R)-1-hydroxyethyl)-4-oxoazetidin-2-yl)-3-oxopentanoate (R)-4-Nitrobenzyl 2-diazo-4-((2R,3S)-3-((R)-1-hydroxy-ethyl)-4-oxoazetidin-2-yl)-3-oxopentanoate (3S,4R)-3-[(1R)-1-Hydroxyethyl]-4-[(1R)-1-Methyl-3-diazo-3-(p-nitrobenzyloxycarbonyl)-2-oxopropyl]az (3S,4R)-3-[(1R)-1-Hydroxyethyl]-4-[(1R)-1-methyl-3-diazo-3-(p-nitrobenzyloxycarbonyl)-2-oxopropyl]azetidin-2-one (3S,4R)-3-[(1R)-1-Hydroxyethyl]-4-[(1R)-1-methyl-3-diazo-3-(4-nitrobenzyloxycarbonyl)-2-oxopropyl]azetidin-2-one 2-Azetidinebutanoic-a-14C acid, a-diazo-3-(1-hydroxyethyl)-g-methyl-b,4-dioxo-,(4-nitrophenyl)methyl ester, [2R-[2a(R),3b(R)]]- (9CI)
CAS	90822-24-5 158299-05-9 137391-68-5
EINECS	1312995-182-4
InChI	InChI=1/C16H18BrNO3/c1-11(17)14(19)18-15(20)12-7-3-4-8-13(12)21-16(18)9-5-2-6-10-16/h3-4,7-8,11H,2,5-6,9-10H2,1H3

BR-Comp - Physico-chemical Properties

Molecular Formula	C17H18N4O7
Molar Mass	390.35
Density	1.48g/cm³
Melting Point	73-75℃
Boling Point	485°C at 760 mmHg
Flash Point	247.1°C
Vapor Presure	1.47E-09mmHg at 25°C
Storage Condition	-196°C
Refractive Index	1.613
Physical and Chemical Properties	Light yellow crystalline powder
Use	Synthesis of a series of intermediates and nuclei of meropenem

BR-Comp - Introduction

3-(2-Bromo-1-oxopropyl)-spiro[2H-1,3-benzoxazine-2,1 '-cyclohexan]-4(3H)-one is an organic compound with the following properties:

Nature:
-Appearance: Colorless or light yellow crystal
-Molecular formula: C13H15BrN2O2
-Molecular weight: 319.18g/mol
-Melting point: 120-122°C
-Boiling Point: Not Applicable
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dimethyl sulfoxide

Use:
3-(2-Bromo-1-oxopropyl)-spiro[2H-1,3-benzoxazine-2,1 '-cyclohexan]-4(3H)-one has certain application value in organic synthesis. It is commonly used as a tetrahydroazine derivative of intermittent catalyst and can participate in some negative oxygen ion and free radical reactions. In addition, the compound can also be used as a pharmaceutical intermediate.

Method:
This compound can be synthesized through the functional groups present in the molecule. One common preparation method involves the Wick reaction (Vilsmeier-Haack reaction) and multicomponent reactions. The specific preparation method can refer to the relevant organic chemical synthesis manual or professional literature.

Safety Information:
Because no detailed toxicity data are publicly available, the use and handling of this compound requires following routine safe practices, including wearing appropriate personal protective equipment, working in a well-ventilated laboratory, and following closely the recommendations on the relevant Chemical Safety Data Sheet (MSDS). In case of accidental inhalation, swallowing or skin contact, seek medical attention immediately.

Last Update：2024-04-09 15:18:00