Molecular Formula | C20H38O12 |
Molar Mass | 470.51 |
Density | 1.179±0.06 g/cm3(Predicted) |
Boling Point | 601.8±55.0 °C(Predicted) |
pKa | 3.97±0.10(Predicted) |
Storage Condition | 2-8°C |
In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |