ASARININ(P)
(-)-Episesamin
CAS: 133-04-0;133-05-1
Molecular Formula: C20H18O6
ASARININ(P) - Names and Identifiers
ASARININ(P) - Physico-chemical Properties
| Molecular Formula | C20H18O6 |
| Molar Mass | 354.35 |
| Density | 1.385±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 120-122°C(lit.) |
| Boling Point | 504.4±50.0 °C(Predicted) |
| Specific Rotation(α) | -118.6°(chloroform) |
| Flash Point | 212.3°C |
| Solubility | Soluble in boiling methanol, ethanol, chloroform, acetone and benzene. Almost insoluble in water. |
| Vapor Presure | 8.38E-10mmHg at 25°C |
| Appearance | White crystal |
| Storage Condition | -20°C |
| Refractive Index | 1.622 |
| MDL | MFCD00198067 |
ASARININ(P) - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29329990 |
ASARININ(P) - Reference
| Reference Show more | 1. Wang Zhiqing Song Jia Ma Haiqin et al. Determination and comparison of main active ingredients in Asarum from different habitats [J]. Chinese herbal medicine 2020(3). 2. Ma Xuemei, Wang Yuzhen, Gao Shuang, et al. Multi-index comprehensive weighted evaluation optimizes the extraction and purification process of Mahuang Fuzi Asarum Decoction [J]. Liaoning Journal of Traditional Chinese Medicine, 2019, v.46;No.510(11):157-162. 3. Lu Yang, Zhao Rong, Li Jiaying, et al. Comparing the quality of wild and cultivated Liao Asarum by total volatile oil and asarum content [J]. Modern Distance Education of Chinese Medicine, 2018, 016(011):85-86. 4. Ma Xuemei, Li Lingjun, Xie Huichao, etc. Study on Dynamic Changes of Extraction of Six Active Components from Mahuang Xixin Fuzi Decoction [J]. Shandong Science, 2018, 31(006):11-17. |
ASARININ(P) - Introduction
(-)-Episesamin is a molecule that is a mirror image of each other in its three-dimensional optical properties and is also known as tetramethylpyrazine glycoside. Its chemical name is (±)-ligustilide.
Nature:
(-)-Episesamin is a colorless crystalline solid with a special aroma and pungent odor. It is soluble in non-polar solvents such as ether, benzene and petroleum ether, but poorly soluble in water. It has optical properties, but because it contains two stereoisomers, its overall optical rotation is zero.
Use:
(-)-Episesamin is commonly used as the active ingredient in traditional medicine, mainly for the treatment of dysmenorrhea, headache and blood flow disorders and other symptoms. It is also used as a food and flavor additive to increase the aroma and taste of products.
Preparation Method:
(-)-Episesamin is usually extracted from Chuanxiong (Schizonepeta tenuifolia). First, Chuanxiong was crushed and soaked, and then extracted with an organic solvent such as ether to obtain an extract containing (-)-Episesamin. Next, pure (-)-Episesamin crystals can be obtained by separation methods such as evaporation and crystallization.
Safety Information:
(-)-Episesamin is considered a relatively safe compound, but it still needs to follow appropriate use and dosage regulations. During the application process, care needs to be taken to avoid contact with the skin and eyes to prevent irritation and allergic reactions. For people with allergies, it may cause allergic symptoms. Relevant regulations and precautions should be followed during use, and correct experimental operations and safety measures should be followed.
Nature:
(-)-Episesamin is a colorless crystalline solid with a special aroma and pungent odor. It is soluble in non-polar solvents such as ether, benzene and petroleum ether, but poorly soluble in water. It has optical properties, but because it contains two stereoisomers, its overall optical rotation is zero.
Use:
(-)-Episesamin is commonly used as the active ingredient in traditional medicine, mainly for the treatment of dysmenorrhea, headache and blood flow disorders and other symptoms. It is also used as a food and flavor additive to increase the aroma and taste of products.
Preparation Method:
(-)-Episesamin is usually extracted from Chuanxiong (Schizonepeta tenuifolia). First, Chuanxiong was crushed and soaked, and then extracted with an organic solvent such as ether to obtain an extract containing (-)-Episesamin. Next, pure (-)-Episesamin crystals can be obtained by separation methods such as evaporation and crystallization.
Safety Information:
(-)-Episesamin is considered a relatively safe compound, but it still needs to follow appropriate use and dosage regulations. During the application process, care needs to be taken to avoid contact with the skin and eyes to prevent irritation and allergic reactions. For people with allergies, it may cause allergic symptoms. Relevant regulations and precautions should be followed during use, and correct experimental operations and safety measures should be followed.
Last Update：2024-04-09 21:04:16
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