APIOSIDE
Apiin
CAS: 26544-34-3
Molecular Formula: C26H28O14
APIOSIDE - Names and Identifiers
APIOSIDE - Physico-chemical Properties
| Molecular Formula | C26H28O14 |
| Molar Mass | 564.49 |
| Density | 1.74±0.1 g/cm3(Predicted) |
| Melting Point | 230°C (dec.) |
| Boling Point | 942.2±65.0 °C(Predicted) |
| Specific Rotation(α) | (c, 0.12 in MeOH)-130 |
| Solubility | Soluble in methanol, DMSO and other solvents, insoluble in petroleum ether, chloroform and other solvents. |
| Appearance | Yellow crystal |
| Color | Pale Yellow |
| pKa | 6.11±0.40(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Stability | Hygroscopic |
| MDL | MFCD00016941 |
| Physical and Chemical Properties | Chemical properties yellow crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from celery seed, Noble spring yellow chrysanthemum Anthemis nobilis, Celery Apium graveolens, maternal chrysanthemum matridia camomila [Syn. Matricaria recuJita], small nest dish ircia hirsuta, parsley leaf. |
| Use | Use of celery glycosides with sedative, spasmolytic effect. For content determination/identification/pharmacological experiments. |
APIOSIDE - Risk and Safety
| WGK Germany | 1 |
| FLUKA BRAND F CODES | 3-10 |
| HS Code | 29389090 |
APIOSIDE - Reference
| Reference Show more | 1. Liu Linlin Li Hui He Dan Wang Menglei Liu Zhenli Shu Yi Zhao Siyu Liu Yuan Yan. Analysis and comparison of metabolism and excretion process of extracts from pericarpium citri reticulatae and pericarpium citri reticulatae in rat urine and feces by RRLC-QqQ-MS ~ n method [J]. Chinese Journal of Traditional Chinese Medicine, 2018, 43(22):4519-4527. 2. Huang Jin-Li, Wei Xian-E, Su Zhao-lan, et al. Simultaneous determination of apigenin and 3-methoxyapigenin in celery seed extract by high performance liquid chromatography [J]. Journal of Food Safety and quality testing, 2020, 011(001):253-257. 3. [IF = 3.645] Guoyan Liu et al."Isolation, purification, and identification. var. dulce Mill./Pers.) no. J Sep Sci. 2017 Jan;40(2):472-479 4. [IF = 3.361] Yuhao Zhang et al."An integrated approach for structural characterization of Gui Ling Ji by traveling wave ion mobility mass spectrometry and molecular network."Rsc Adv. 2021 Apr;11(26):15546-15556 5. [IF=2.629] Li Baolin et al."Phytochemical Analysis Using UPLC-MS/MS Combined with Network Pharmacology Methods to Explore the Biomarkers for the Quality Control of Lingguizhugan Decoction."Evid-Based Compl Alt. 2021;2021:7849032 6. [IF=4.38] Zheng Bingxin et al."Rhoifolin from Plumula Nelumbinis exhibits anti-cancer effects in pancreatic cancer via AKT/JNK signaling pathways."Sci Rep-Uk. 2022 Apr;12(1):1-14 |
APIOSIDE - Uses and methods of synthesis
Overview
flavonoids in celery are excellent active oxygen scavengers and lipid antioxidants, with a variety of biological activities, such as antioxidant, antibacterial, antiviral, anticancer, anti-aging and so on.
biological activity
Apiin is one of the main components of the leaves of Apium graveolens, which has anti-inflammatory properties. Apiin inhibited the production of nitrite (NO) in vitro (IC50=0.08 mg/mL) and iNOS expression in LPS-activated J774.A1 cells (IC50=0.049 mg/mL).
Last Update：2024-04-10 22:29:15
APIOSIDE - Reference Information
| overview | flavonoids in celery are excellent active oxygen scavengers and lipid antioxidants, with a variety of biological activities, such as antioxidant, antibacterial, antiviral, anti-cancer, anti-aging and other effects. |
| biological activity | Apiin is one of the main components of Apium graveolens leaves and has anti-inflammatory properties. Apiin can inhibit nitrite (NO) production in vitro (IC50=0.08 mg/mL) and iNOS expression in LPS-activated J774.A1 cells (IC50=0.049 mg/mL). |
| chemical properties | yellow crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from celery seeds, noble spring chrysanthemum Anthemis nobilis, parsley Apium graveolens, mother chrysanthemum Matricaria chamomilla [Syn. Matricaria recuJita], small nest vegetable ircia hirsuta, wrinkled leaf parsley. |
| use | apigenin has sedative and antispasmodic effects. used for content determination/identification/pharmacological experiment, etc. |
Last Update：2024-04-09 02:00:01
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