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89324-16-3

4-oxo-1,4-dihydropyridine-3-carbonitrile

CAS: 89324-16-3

Molecular Formula: C6H4N2O

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89324-16-3 - Names and Identifiers

Name 4-oxo-1,4-dihydropyridine-3-carbonitrile
Synonyms LogP
4-Hydroxynicotinonitrile
4-hydroxynicotinonitrile
4-Hydroxy-3-pyridinecarbonitrile
4-hydroxypyridine-3-carbonitrile
Nicotinonitrile, 4-hydroxy- (7CI)
3-Pyridinecarbonitrile, 4-hydroxy-
3-pyridinecarbonitrile, 4-hydroxy-
4-oxo-1,4-dihydropyridine-3-carbonitrile
3-pyridinecarbonitrile, 1,4-dihydro-4-oxo-
4-Hydroxy-1,4-dihydropyridine-3-carbonitrile
CAS 89324-16-3
InChI InChI=1/C6H4N2O/c7-3-5-4-8-2-1-6(5)9/h1-2,4H,(H,8,9)

89324-16-3 - Physico-chemical Properties

Molecular FormulaC6H4N2O
Molar Mass120.11
Density1.27g/cm3
Boling Point244.6°C at 760 mmHg
Flash Point101.7°C
Vapor Presure0.0302mmHg at 25°C
Storage Condition2-8°C
Refractive Index1.571

89324-16-3 - Introduction

4-oxo-1 (4-oxo-1) is an organic compound with a chemical formula of C6H4N2O and a structural formula:

H
|
H3C-C(=O)N-C≡N

The following is a description of the properties, uses, preparation methods and safety information of the compound:

Nature:
-Appearance: A white or off-white solid
-Melting point: about 162-165°C
-Solubility: Soluble in most organic solvents, such as dimethyl sulfoxide, dimethyl formamide and methanol

Use:
- 4-oxo-1, is an important intermediate for the synthesis of a variety of drugs, especially for the synthesis of calcium ion antagonists.
-It can also be used to synthesize biologically active compounds, such as antibacterial agents and anti-tumor drugs.

Preparation Method:
A commonly used preparation method is obtained by reacting hydrogen cyanide with 2-aminopyridone under the catalysis of dimethyl sulfoxide (DMSO). The specific steps are as follows:
1. Dissolve 2-aminopyridone in DMSO.
2. Add hydrogen cyanide at low temperature and stir the reaction.
3. After the reaction is completed, the reaction solution is processed and purified to obtain 4-oxo-1, the product.

Safety Information:
- 4-oxo-1, no special safety problems are reported under normal use conditions.
-As an organic compound, use is subject to general laboratory safety practices, such as wearing appropriate personal protective equipment, avoiding inhalation, contact with skin, etc.
-When handling this compound or related compounds, care should be taken to prevent it from entering the eyes, mouth or inhalation, and avoid direct skin contact. If contact occurs, flush the affected area immediately with plenty of water and seek medical attention if you feel unwell.
Last Update:2024-04-09 02:00:49
89324-16-3
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Shanghai Macklin Biochemical Co., Ltd
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: 4-Hydroxynicotinonitrile Visit Supplier Webpage Request for quotation
CAS: 89324-16-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Nicotinonitrile, 4-hydroxy- (7CI) Request for quotation
CAS: 89324-16-3
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Nicotinonitrile, 4-hydroxy- (7CI) Visit Supplier Webpage Request for quotation
CAS: 89324-16-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Nicotinonitrile, 4-hydroxy- (7CI) Visit Supplier Webpage Request for quotation
CAS: 89324-16-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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