872511-34-7
NVP-BGJ398
CAS: 872511-34-7
Molecular Formula: C26H31Cl2N7O3
872511-34-7 - Names and Identifiers
| Name | NVP-BGJ398 |
| Synonyms | BGJ 398 NVP-BGJ398 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea |
| CAS | 872511-34-7 |
872511-34-7 - Physico-chemical Properties
| Molecular Formula | C26H31Cl2N7O3 |
| Molar Mass | 560.48 |
| Density | 1.354 |
| Melting Point | >211°C (dec.) |
| Boling Point | 747.9±60.0 °C(Predicted) |
| Appearance | Shape White solid, color White |
| pKa | 11.02±0.70(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
| Physical and Chemical Properties | Bioactive BGJ398 (NVP-BGJ398) is an effective and selective FGFR inhibitor, acting on FGFR1/2/3,IC50 is 0.9 nM/1.4 nM/1 nM, acting on FGFR is more than 40 times more selective than acting on FGFR4 and VEGFR2, and has almost no inhibitory activity on Abl, Fyn, Kit, Lck, Lyn and Yes. |
| Use | Uses BGJ 398 is a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinases. |
872511-34-7 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.784 ml | 8.921 ml | 17.842 ml |
| 5 mM | 0.357 ml | 1.784 ml | 3.568 ml |
| 10 mM | 0.178 ml | 0.892 ml | 1.784 ml |
| 5 mM | 0.036 ml | 0.178 ml | 0.357 ml |
Last Update：2024-01-02 23:10:35
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Multiple SpecificationsSpot supply
Product Name: BGJ-398; NVP-BGJ398 Visit Supplier Webpage Request for quotationCAS: 872511-34-7
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Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
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Product Name: BGJ-398 Visit Supplier Webpage Request for quotationCAS: 872511-34-7
Tel: +16314854226
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Product Name: NVP-BGJ398 Visit Supplier Webpage Request for quotationCAS: 872511-34-7
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Product Name: NVP-BGJ398 Visit Supplier Webpage Request for quotationCAS: 872511-34-7
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