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857890-39-2

Lenvatinib mesylate

CAS: 857890-39-2

Molecular Formula: C22H23ClN4O7S

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857890-39-2 - Names and Identifiers

Name Lenvatinib mesylate
Synonyms E7080 Mesylate
Lenvatinib mesylate
lenvatinib Methanesulfonate
4-[3chloro-4-(N'-cyclopropylureido)phenoxy]-7-methoxyquinoline-6-carboxamide methanesulfonate
4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide monomethanesulfonate
CAS 857890-39-2
EINECS 812-398-0

857890-39-2 - Physico-chemical Properties

Molecular FormulaC22H23ClN4O7S
Molar Mass522.95862
Melting Point>220°C (dec.)
AppearanceForm Solid, color White to Off-White
Storage Condition-20°C Freezer
Physical and Chemical PropertiesBioactive Lenvatinib Mesylate (E7080) is a synthetic, orally active inhibitor of tyrosine kinase that inhibits vascular endothelial growth factor receptor (VEGFR1-3), fibroblast growth factor receptor (FGFR1-4), platelet-derived growth factor receptor (PDGFRα), stem cell factor receptor (Kit (c-Kit)), and rearrangement during transfection (RET (c-RET)). Levatinib mesylate has potential anti-tumor activity.
UseApplication of lenvatinib is a multi-target tyrosine kinase inhibitor, which may play a role in a variety of cancers, so Eisai is still in the research of lenvatinib for other cancers, such as hepatocellular carcinoma, Non-small cell lung cancer, melanoma, breast cancer, lymphoma, ovarian cancer, etc., retrieved by the drug ferry data, there are 62 clinical research information related to lenvatinib. In July 2017, Eisai submitted a listing application for the first-line treatment of advanced hepatocellular carcinoma with lenvatinib to the US FDA and the European Drug Administration. In clinical trials, lenvatinib is superior to the current standard therapeutic drug sorafenib for advanced hepatocellular carcinoma.
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 857890-39-2
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MedChemExpress (MCE)
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CAS: 857890-39-2
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: lenvatinib Mesylate Visit Supplier Webpage Request for quotation
CAS: 857890-39-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: LenvatinibMesylate Request for quotation
CAS: 857890-39-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Lenvatinib Mesylate Visit Supplier Webpage Request for quotation
CAS: 857890-39-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: E7080 mesylate Visit Supplier Webpage Request for quotation
CAS: 857890-39-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
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