85187-10-6
Sphingomyelin
CAS: 85187-10-6
Molecular Formula: C41H84N2O6P
85187-10-6 - Names and Identifiers
85187-10-6 - Physico-chemical Properties
| Molecular Formula | C41H84N2O6P |
| Melting Point | 200 - 202°C |
| Solubility | chloroform/methanol: soluble50mg/mL, clear, colorless to faintly yellow (1:1) |
| Appearance | powder |
| Color | white |
| Storage Condition | -20°C |
| Physical and Chemical Properties | Bioactive Sphingomyelin is a kind of eukaryotic Sphingomyelin, which is one of the main components of cell membrane, especially abundant in the membrane myelin of neuronal axons. Sphingomyelin plays an important role in cellular processes, regulation of inflammatory responses and signal transduction. Sphingomyelin metabolism is associated with a variety of central nervous system diseases and Niemann-Pick diseases. |
| Use | Sphingomyelin is a natural ingredient in food. In recent years, sphingomyelin in food has been paid more and more attention, mycotoxins caused by diseases are closely related, so the relationship between sphingomyelin in food and human health has become the characteristics of the current study. At present, the metabolic pathway of sphingomyelin in the human body is not very clear, but studies have shown that its two major metabolites ceramide and sphingosine are involved in cell growth, differentiation, apoptosis and other physiological activities. |
85187-10-6 - Risk and Safety
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 1-8-10 |
85187-10-6 - Uses and methods of synthesis
Biological Function
sphingomyelin is mainly located in the cell membrane, lipoprotein (especially LDL) and other lipid-rich tissue structure, sphingomyelin for the maintenance of cell membrane structure, especially the micro-control function of cell membrane (such as membrane invagination) very important, it regulates the activity of growth factor receptors and supercellular matrix proteins, and provides binding sites for some microorganisms, microbial toxins, Virus. Many extracellular drugs and external stimuli such as tumor necrosis factor (TNF & sigma;), interleukin (IL-1), & gamma; Radiation, interferon (IFN & gamma;) can be activated by the activation of sphingomyelinase to hydrolysis of sphingomyelin, releasing ceramide, ceramide as the second messenger can regulate the activity of several substances: protein kinase C isoenzyme (PKC), protein phosphatase (CAPP) and protein kinase (CAPK).
Target
Human Endogenous Metabolite
in vitro studies
Sphingomyelin metabolism resulting in the production of various interconvertible bioactive sphingolipids or derivatives such as ceramide, diacylglyceride, and sphingosine-1-phosphate. These bioactive lipids act on their specific targets within the cell and regulate various signal transduction pathways, thereby affecting cellular functions.
Sphingomyelin enriched lipid raft mediated cell signaling.
Last Update：2024-04-10 22:29:15
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