851211-74-0
1H-Indole-6-carboxylic acid, hydrazide
CAS: 851211-74-0
Molecular Formula: C9H9N3O
851211-74-0 - Names and Identifiers
851211-74-0 - Physico-chemical Properties
| Molecular Formula | C9H9N3O |
| Molar Mass | 175.19 |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
851211-74-0 - Introduction
1H-Indole-6-hydrazide acid (hydrazide) is an organic compound. It has the formula C9H8N2O and has an indole group and a formylhydrazine group.
In terms of properties, 1H-Indole-6-carboxylic acid, hydrazide is a white crystalline solid, soluble in some common organic solvents such as methanol and dimethyl sulfoxide.
1H-Indole-6-carboxylic acid, hydrazide is mainly used as an intermediate in organic synthesis. It can be used as a hydrazide reagent to participate in various important reactions, such as hydrazide substitution reaction, reduction reaction, coupling reaction, etc. In addition, 1H-Indole-6-carboxylic acid, hydrazide can also be used to synthesize pyrazoloindole compounds, which are of great significance for pharmaceutical and pesticide research.
1H-Indole-6-carboxylic acid, hydrazide can be prepared by the reaction of indole -7-one with hydrazine. Specifically, indol-7-one is reacted with an excess of hydrazine under basic conditions to give 1H-Indole-6-carboxylic acid, hydrazide. The reaction process can be carried out at atmospheric pressure or at low temperature.
Regarding safety information, 1H-Indole-6-carboxylic acid, hydrazide has a lower risk under correct operation. However, it is an irritating compound and has an irritating effect on the eyes, skin and respiratory tract. Therefore, during use, contact with skin and eyes should be avoided and appropriate protective equipment must be worn.
In terms of properties, 1H-Indole-6-carboxylic acid, hydrazide is a white crystalline solid, soluble in some common organic solvents such as methanol and dimethyl sulfoxide.
1H-Indole-6-carboxylic acid, hydrazide is mainly used as an intermediate in organic synthesis. It can be used as a hydrazide reagent to participate in various important reactions, such as hydrazide substitution reaction, reduction reaction, coupling reaction, etc. In addition, 1H-Indole-6-carboxylic acid, hydrazide can also be used to synthesize pyrazoloindole compounds, which are of great significance for pharmaceutical and pesticide research.
1H-Indole-6-carboxylic acid, hydrazide can be prepared by the reaction of indole -7-one with hydrazine. Specifically, indol-7-one is reacted with an excess of hydrazine under basic conditions to give 1H-Indole-6-carboxylic acid, hydrazide. The reaction process can be carried out at atmospheric pressure or at low temperature.
Regarding safety information, 1H-Indole-6-carboxylic acid, hydrazide has a lower risk under correct operation. However, it is an irritating compound and has an irritating effect on the eyes, skin and respiratory tract. Therefore, during use, contact with skin and eyes should be avoided and appropriate protective equipment must be worn.
Last Update：2024-04-09 20:48:19
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