848821-61-4

848821-61-4 - Names and Identifiers

Name	Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-
Synonyms	(S)-α,α-BIS(3,5-BIS(TRIFLUOROMET (S)-α,α-[3,5-Bis(trifluoroMethyl)phenyl]prolinol triMethylsilyl ether (S)-2-[(Bis(3,5-bis(trifluoroMethyl)phenyl)triMethylsilanyloxy)Methyl]pyrrolidine Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)- (S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)- (S)-2-[(Bis(3,5-Bis(Trifluoromethyl)Phenyl)Trimethylsilanyloxy)Methyl]Pyrrolidine, (S)-2-[(Bis(3,5-Bis(Trifluoromethyl)Phenyl)Trimethylsilyloxy)Methyl]Pyrrolidine, (S)-Α,Α-[3,5-Bis(Trifluoromethyl)Phenyl]Prolinol Trimethylsilyl Ether (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilanyloxy)methyl]pyrrolidine, (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine, (S)-α,α-[3,5-Bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether
CAS	848821-61-4

848821-61-4 - Physico-chemical Properties

Molecular Formula	C24H23F12NOSi
Molar Mass	597.51
Density	1.319±0.06 g/cm3(Predicted)
Melting Point	48-56°C
Boling Point	382.4±37.0 °C(Predicted)
Flash Point	110°C
pKa	9.34±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

848821-61-4 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3

848821-61-4 - Introduction

Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-, also known as (2S)-Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless to light yellow liquid
-Molecular formula: C24H26F6NOSi
-Molecular weight: 500.55g/mol
-Melting point: No data
-Boiling Point: No data
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane

Use:
- Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-is often used as a chiral catalyst in chemical synthesis
-It is widely used in organic synthesis reactions, such as asymmetric hydrogenation, asymmetric methylation, asymmetric olefin cyclization, etc.

Preparation Method:
- Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-can be prepared by reacting compounds containing corresponding functional groups
-Usually the silicon ether compound is reacted with a chiral amine to form a chiral silicon ether

Safety Information:
- Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-has limited safety information, so general laboratory safety operation specifications should be followed when using
-It should be operated under good ventilation and avoid contact with skin and eyes
-Wear appropriate protective equipment such as gloves and goggles when using it
-In case of accidental inhalation or ingestion, seek medical attention immediately and provide the technical safety data sheet to the doctor for reference

Please note that this is only an introduction of some basic information about Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-specific uses and preparation methods may require more detailed research and practice. When using this substance, always consult the relevant literature and reliable sources and strictly observe the relevant safety procedures.

Last Update：2024-04-10 22:29:15