8021-29-2
Pineneedle Oil
CAS: 8021-29-2
Molecular Formula:
8021-29-2 - Names and Identifiers
8021-29-2 - Physico-chemical Properties
| Density | 0.909g/mLat 25°C(lit.) |
| Boling Point | 132°C(lit.) |
| Flash Point | 110°F |
| Appearance | liquid |
| Refractive Index | n20/D 1.4750(lit.) |
| Physical and Chemical Properties | Almost colorless or yellowish liquid, with a balsam aroma of needles. Soluble in diethyl phthalate, benzyl benzoate, most non-volatile oil and mineral oil, almost insoluble loss: propylene glycol and glycerol. It is unstable to alkali and strong acid, and changes properties in weak acid. |
| Use | Uses spices. Mainly used in alcohol. |
8021-29-2 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R10 - Flammable R36/38 - Irritating to eyes and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 2 |
| RTECS | LK5100000 |
8021-29-2 - Pine Needle Oil Induces Apoptosis of HepG2 Cells and Its Effect on Telomerase Activity
From Wanfang Medicine
Author:
Wei Fengxiang ,< a href = "https://xueshu.baidu.com/s?wd=author: (Li Meiyu) & tn = SE_baiduxueshu_c1gjeupa & ie = utf-8 & SC _f_para = SC _hilight = person" target = "_blank"> Li Meiyu ,< a href = "https://xueshu.baidu.com/s?wd=author: (song yuhong) & tn = SE_baiduxueshu_c1gjeupa & ie = utf-8 & SC _f_para = SC _hilight = person" target = "_blank"> song yuhong , Li hongzhi
Summary:
objective: to study the effect of pine needle oil on human hepatoma HepG2 cells. Methods: pine needle oil was extracted by steam distillation, and its composition was GC-MS analyzed. After different concentrations of pine needle oil were treated with HepG2 cells, the growth inhibition rate of HepG2 cells was determined by MTT method. Morphological changes of apoptosis were observed under HE staining and electron microscope. Flow cytometry was used to detect apoptosis rate. Flow cytometry was used to examine the expression level of bcl-2 genes. TRAP method was used to determine the changes of telomerase activity. Results: MTT method proved that pine needle oil can significantly inhibit the growth of HepG2 cells, and the inhibition rate is positively correlated with the drug concentration, showing obvious dose-effect and time-effect relationship. Apoptosis can be detected by flow cytometry, and 0.125~8 mg/L pine needle oil can cause HepG2 cell apoptosis in a time-dependent and dose-dependent manner. Typical apoptosis characteristics such as nuclear concentration and nuclear fragmentation can be observed under electron microscope. Pine needle oil induces apoptosis and decreases the expression level of telomerase activity and bcl-2. Conclusion: pine needle oil induces apoptosis of hepatoma HepG2 cells and inhibits telomerase activity, which bcl-2 participates in the regulation of telomerase activity during apoptosis of hepatoma HepG2 cells induced by pine needle oil.
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keywords:
pine needle oil; HepG2 cells; Apoptosis; bcl-2 gene; Telomerase
DOI:
10.3321/j.issn:1001-4454.2008.08.031
cited:
Year:
2008
Last Update：2024-01-02 23:10:35
8021-29-2 - A water vapor extraction and analysis of black pine needle oil device and its analysis method.
from Baidu library
patent type:
patent for invention
application (patent) number:
CN201910081014.3
date of application:
20190128
public/announcement number:
CN109762650A
date of publication/announcement:
20190517
Applicant (patentee):
Yangzhou Industrial Vocational and Technical College
Inventor:
yue jinfang , Wang Xueyuan , Luo Zhichen ,< a href = "https://xueshu.baidu.com/s?wd=author: (Zuo Chunli) & tn = SE_baiduxueshu_c1gjeupa & ie = utf-8 & SC _f_para = SC _hilight = person" target = "_blank"> Zuo Chunli
national and provincial code:
CN321003
Summary:
The present invention discloses a water vapor method extraction and analysis of black pine pine needle oil device and its analysis method, including a main body, the inside of the main body is provided with a distillation frame, the inside of the distillation frame is fixedly connected with a reaction kettle, The top of the left side of the reaction kettle is provided with a material inlet, the top of the inner wall of the reaction kettle is fixedly connected with a fixed rod, and the bottom of, the inside of the motor frame is fixedly connected with a motor, the output shaft of the motor is fixedly connected with a coupling, and the motor is fixedly connected with a rotating shaft through the coupling. The present invention relates to the technical field of plant extraction. The water vapor extraction and analysis device for pine needle oil and its analysis method achieve the goal of adding pine needles to the reaction kettle, adding water, heating and distillation of the reaction kettle, and fully stirring the materials at the same time, so that the pine needles are refined more fully, reducing the waste of biological materials, accelerating the distillation rate, and thus improving the production efficiency.
Last Update：2023-08-16 22:23:51
8021-29-2 - Preparation and Properties of Pine Needle Oil Microcapsules
Author:
Qian xingyue , Wang dongfang , Ji Junling , Chen Qun
Summary:
using gelatin/modified gum arabic as wall material and pine needle oil as core material, pine needle oil microcapsules were prepared by composite coagulation method. The optimum reaction conditions for preparing pine needle oil microcapsules are as follows: gelatin/modified Arabic gum ratio is 1.25:1, mass fraction is 0.6%,pH = 4.1, reaction time is 75min, stirring speed is 300rpm, curing temperature is 45 ℃, curing time is 10h. Optical microscope (OM), scanning electron microscope (SEM), Fourier transform infrared spectrometer (FTIR) and thermogravimetric analyzer (DTG-TA) were used to characterize the morphology and thermal properties of pine needle oil microcapsules. The results showed that the prepared pine needle oil microcapsules had uniform particle distribution and good thermal stability and slow release properties. The fabric finished by pine needle oil microcapsules shows good slow release performance and water washing resistance.
keywords:
pine needle oil composite condensation microcapsule aromatic fabric
cited:
Last Update：2023-08-16 22:24:45
8021-29-2 - Reference Information
| FEMA | 2905 | PINE NEEDLE OIL (ABIES SPP.) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| content analysis | accurately weigh about 2g of sample and measure according to ester determination method (OT-18). The equivalent factor (e) in the calculation is 98.15. From this, the ester content of bornyl acetate is calculated. |
| toxicity | GRAS(FEMA)LD5010200mg/kg (rat, oral). |
| usage limit | FEMA(mg/kg): soft drink 1.5; Cold drink 0.62; Candy 5.2; Baked food 2.7. Moderate is limited (F'DA § 172.210,2000). |
| use | spices. Mainly used for alcohol. |
| Production method | The needles and branches of the pine plant Abies sibirica are obtained by steam distillation. The oil yield of needles is about 3%, and that of branches is about 1.2%. Mainly produced in Russia. |
Last Update：2024-04-09 15:16:44
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Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
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Product Name: OilsSiberian fir Visit Supplier Webpage Request for quotationCAS: 8021-29-2
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: Pineneedle Oil Request for quotation
CAS: 8021-29-2
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 8021-29-2
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
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