78-39-7
Triethyl orthoacetate
CAS: 78-39-7
Molecular Formula: C8H18O3
78-39-7 - Names and Identifiers
78-39-7 - Physico-chemical Properties
| Molecular Formula | C8H18O3 |
| Molar Mass | 162.23 |
| Density | 0.885 g/mL at 25 °C (lit.) |
| Boling Point | 142 °C (lit.) |
| Flash Point | 97°F |
| Water Solubility | SLIGHTLY SOLUBLE |
| Vapor Presure | 3.4 hPa (20 °C) |
| Appearance | Liquid |
| Color | Clear colorless to slightly yellow |
| BRN | 506201 |
| Storage Condition | Store below +30°C. |
| Sensitive | Moisture Sensitive |
| Explosive Limit | 0.9-7.0%(V) |
| Refractive Index | n20/D 1.396(lit.) |
| Physical and Chemical Properties |
|
| Use | For the preparation of trans trisubstituted alkene and chiral Allene and other vinyl preparations and dyes, raw materials for the pharmaceutical industry |
78-39-7 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R10 - Flammable R36/38 - Irritating to eyes and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S16 - Keep away from sources of ignition. |
| UN IDs | UN 3272 3/PG 3 |
| WGK Germany | 1 |
| RTECS | KJ4075000 |
| TSCA | Yes |
| HS Code | 29159080 |
| Hazard Class | 3 |
| Packing Group | III |
78-39-7 - Reference Information
| LogP | 2.6 at 20℃ |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Use | triethyl ortho-acetate is an important intermediate in the synthesis of ethyl dichloro-Chrysanthemum. It is used for the preparation of Alene preparations such as trans-trisubstituted alkene and chiral allene, and the raw materials of dyes and pharmaceutical industry It is an intermediate for the synthesis of medicines, dyes and pesticides. |
| production method | triethyl ortho-acetate and trimethyl ortho-acetate are prepared by pumping acetonitrile, toluene and anhydrous ethanol into a salt-forming pot, cooling to -10 ~-5 ℃, feeding the amount of dry hydrogen chloride, keeping the salt formation temperature -5~0 ℃, when the hydrogen chloride is finished, the reaction at 0 ℃ for 1H, then keep the temperature at 0~20 ℃ for 0.5h, move to alcoholysis Pan, carry out salt formation reaction, keep the temperature at 20~25 ℃, react with stirring, about 12h, the intermediate imino ether hydrochloride is gradually precipitated out, cooled to 0~5 ℃, then the pre-cooled anhydrous ethanol and Thymol blue indicator are added, and the stirring is accelerated. At the same time, ammonia gas is slowly introduced into the alcoholysis material for neutralization, observe the color change of the indicator until it changes from red to yellow without turning red, pH = 3.6, At this time, the aeration is finished, and the alcoholysis reaction is carried out at 40 ℃ for about 8~9H. The material is cooled, ammonium chloride is removed by filtration through a centrifuge, and the filtrate is pumped to the neutralization pot, and 17% sodium ethoxide ethanol solution is added, adjust the solution pH = 8~9, the alcoholate is pumped into the distillation pot atmospheric distillation, control the temperature at 75 deg C to recover ethanol, the residual liquid is cooled and filtered to remove acetamide, sodium chloride solids, after washing with 1% Na2CO3 solution and layering, the oil layer is distilled under reduced pressure, toluene is distilled out first, and then the 88-98 ℃/0.07MPa fraction is collected as triethyl orthoacetate. Reaction equation: CH3CN C2H5OH[HCl]→ CH3C(OCH5)3 NH4Cl |
| autoignition temperature | 455°C |
Last Update：2024-04-09 19:05:15
Supplier List
Featured ProductsSpot supply
Product Name: Triethyl orthoacetate Visit Supplier Webpage Request for quotationCAS: 78-39-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Triethyl orthoacetate Request for quotation
CAS: 78-39-7
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 78-39-7
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Triethyl orthoacetate Request for quotationCAS: 78-39-7
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: Triethyl orthoacetate Request for quotationCAS: 78-39-7
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 1,1,1-Triethoxyethane Request for quotationCAS: 78-39-7
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Triethyl orthoacetate Visit Supplier Webpage Request for quotationCAS: 78-39-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Triethyl orthoacetate Visit Supplier Webpage Request for quotationCAS: 78-39-7
Tel: +86-531-82316028
Email: sales@zsscm.com.cn
Mobile: +8615726167122
Spot supply
Product Name: Triethyl orthoacetate Visit Supplier Webpage Request for quotationCAS: 78-39-7
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: Triethyl orthoacetate Request for quotation
CAS: 78-39-7
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 78-39-7
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Featured ProductsSpot supply
Product Name: Triethyl orthoacetate Visit Supplier Webpage Request for quotationCAS: 78-39-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Triethyl orthoacetate Request for quotation
CAS: 78-39-7
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 78-39-7
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Triethyl orthoacetate Request for quotationCAS: 78-39-7
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: Triethyl orthoacetate Request for quotationCAS: 78-39-7
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 1,1,1-Triethoxyethane Request for quotationCAS: 78-39-7
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Triethyl orthoacetate Visit Supplier Webpage Request for quotationCAS: 78-39-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Triethyl orthoacetate Visit Supplier Webpage Request for quotationCAS: 78-39-7
Tel: +86-531-82316028
Email: sales@zsscm.com.cn
Mobile: +8615726167122
Spot supply
Product Name: Triethyl orthoacetate Visit Supplier Webpage Request for quotationCAS: 78-39-7
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: Triethyl orthoacetate Request for quotation
CAS: 78-39-7
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 78-39-7
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
View History
78-39-7
Titanium dioxide,rutile
Demethylnobiletin
1-Bromo-2-ethylbutane (stabilized with Copper chip)
12036-37-2
H-BETA-MEALA-OH HCL
635680-54-5
乙基安定磷
310-93-0
CYCLOBUTANE CARBOXYLIC ACID ETHYL ESTER
Titanium dioxide,rutile
Demethylnobiletin
1-Bromo-2-ethylbutane (stabilized with Copper chip)
12036-37-2
H-BETA-MEALA-OH HCL
635680-54-5
乙基安定磷
310-93-0
CYCLOBUTANE CARBOXYLIC ACID ETHYL ESTER