769944-78-7
1-N-Boc-4-(4-Bromophenyl)piperidine
CAS: 769944-78-7
Molecular Formula: C16H22BrNO2
769944-78-7 - Names and Identifiers
769944-78-7 - Physico-chemical Properties
| Molecular Formula | C16H22BrNO2 |
| Molar Mass | 340.26 |
| Density | 1.283±0.06 g/cm3(Predicted) |
| Boling Point | 398.5±42.0 °C(Predicted) |
| Flash Point | 194.8 °C |
| pKa | -1.75±0.40(Predicted) |
| Storage Condition | 2-8°C |
| MDL | MFCD09878774 |
769944-78-7 - Introduction
1-N-Boc-4-(4-Bromophenyl)piperidine is an organic compound with the chemical formula C17H23BrN2O2. It is a white crystalline solid, stable at room temperature. The following is a description of some information about the properties, uses, preparation and safety of the compound:
Nature:
-Appearance: White crystalline solid
-Molecular weight: 366.28g/mol
-melting point: about 70-75 ℃
-Solubility: Insoluble in water, soluble in organic solvents such as chloroform, dichloromethane, ethanol, etc.
-Preservation: It should be protected from light and sealed, and stored in a dry and cool place
Use:
- 1-N-Boc-4-(4-Bromophenyl)piperidine is an important intermediate, which is widely used in organic synthesis, especially in the synthesis of peptides, drugs and natural products.
-It can be used as an amino protective agent in organic synthesis to protect the amino group during the synthesis of polypeptide compounds to prevent unnecessary reactions.
Preparation Method:
- 1-N-Boc-4-(4-Bromophenyl)piperidine can be prepared by reacting 4-bromobenzoic acid with 1-Boc-4-piperidine ethanol. The specific reaction conditions can be adjusted according to laboratory conditions.
Safety Information:
The -1-N-Boc-4-(4-Bromophenyl)piperidine is not particularly dangerous under routine operation.
-Follow laboratory safety practices and wear appropriate personal protective equipment, such as gloves and goggles, during use.
-Avoid inhalation or contact with skin and eyes, avoid ingestion.
-Please pay attention to the danger of fire and electrostatic discharge when using and storing.
-If inhaled, exposed or ingested, seek medical help immediately and provide the relevant materials and safety data sheets to the doctor for handling.
Please note that this information is only for reference. In specific chemical experiments or applications, operations and measures should be determined according to relevant safety specifications, experimental conditions and specific circumstances.
Nature:
-Appearance: White crystalline solid
-Molecular weight: 366.28g/mol
-melting point: about 70-75 ℃
-Solubility: Insoluble in water, soluble in organic solvents such as chloroform, dichloromethane, ethanol, etc.
-Preservation: It should be protected from light and sealed, and stored in a dry and cool place
Use:
- 1-N-Boc-4-(4-Bromophenyl)piperidine is an important intermediate, which is widely used in organic synthesis, especially in the synthesis of peptides, drugs and natural products.
-It can be used as an amino protective agent in organic synthesis to protect the amino group during the synthesis of polypeptide compounds to prevent unnecessary reactions.
Preparation Method:
- 1-N-Boc-4-(4-Bromophenyl)piperidine can be prepared by reacting 4-bromobenzoic acid with 1-Boc-4-piperidine ethanol. The specific reaction conditions can be adjusted according to laboratory conditions.
Safety Information:
The -1-N-Boc-4-(4-Bromophenyl)piperidine is not particularly dangerous under routine operation.
-Follow laboratory safety practices and wear appropriate personal protective equipment, such as gloves and goggles, during use.
-Avoid inhalation or contact with skin and eyes, avoid ingestion.
-Please pay attention to the danger of fire and electrostatic discharge when using and storing.
-If inhaled, exposed or ingested, seek medical help immediately and provide the relevant materials and safety data sheets to the doctor for handling.
Please note that this information is only for reference. In specific chemical experiments or applications, operations and measures should be determined according to relevant safety specifications, experimental conditions and specific circumstances.
Last Update：2024-04-09 15:17:59
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