756526-04-2
α-Amine-ω-propionic acid octaethylene glycol
CAS: 756526-04-2
Molecular Formula: C19H39NO10
756526-04-2 - Names and Identifiers
756526-04-2 - Physico-chemical Properties
| Molecular Formula | C19H39NO10 |
| Molar Mass | 441.51 |
| Density | 1.128±0.06 g/cm3(Predicted) |
| Boling Point | 547.1±50.0 °C(Predicted) |
| Appearance | solid or viscous liquid |
| pKa | 4.28±0.10(Predicted) |
| Storage Condition | -20°C |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
756526-04-2 - Reference Information
| biological activity | NH2-PEG9-acid is a non-cleavable ADC linker containing 9 units of PEG, which can be used to synthesize antibody-coupled drugs (ADC). NH2-PEG9-acid is also a PROTAC linker, belonging to the PEG class. It can be used to synthesize PROTAC molecules. |
| target | Non-cleavable PEGs |
| in vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Last Update：2024-04-10 22:29:15
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