| Molecular Formula | C24H37ClN2O2 |
| Molar Mass | 421.01578 |
| Melting Point | 91 ±2° |
| Solubility | Soluble in DMSO (up to 25 mg/ml) or ethanol (up to 25 mg/ml) |
| Appearance | powder |
| Color | white |
| Storage Condition | Desiccate at RT |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
| In vitro study | Bepridil hydrochloride hydrate blockades of Ca 2+ -dependent action potentials in vascular smooth muscle of dog coronary artery. Bepridil hydrochloride hydrate blocks Ca currents and Na currents with IC 50 s of 0.5 μM and 30 μM, respectively in cultured ventricular cells. Bepridil hydrochloride hydrate decreases I Ks under blockade of I Kr with E4031 (5 μM), in a concentration-dependent manner. |
| In vivo study | Bepridil hydrochloride hydrate exhibits a half-life of averages 33±15 hours after single-dose administration. |
| WGK Germany | 2 |
| RTECS | UY1162000 |
| Toxicity | LD50 in mice (mg/kg): 1955 orally, 23.5 i.v. (Mauvernay, 1978) |