741717-63-5

741717-63-5 - Names and Identifiers

Name	1H-Pyrazole-4-carboxylicacid, 1-phenyl-3-(trifluoromethyl)-, ethyl ester
Synonyms	Ethyl 1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylate 1-Phenyl-3-trifluoromethyl-1H-pyrazole-4-carboxylicacid ethyl ester 1-Phenyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid ethyl ester 1H-Pyrazole-4-carboxylicacid, 1-phenyl-3-(trifluoromethyl)-, ethyl ester
CAS	741717-63-5

741717-63-5 - Physico-chemical Properties

Molecular Formula	C13H11F3N2O2
Molar Mass	284.23
Storage Condition	2-8°C

741717-63-5 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code	29331990

741717-63-5 - Introduction

1-phenyl-3-(trifluoromethyl)-, ethyl ester is an organic compound with the chemical formula C13H9F3N2O2. The following is a description of its nature, use, formulation and safety information:

Nature:
The 1-phenyl-3-(trifluoromethyl)-, ethyl ester is a solid compound with a benzene ring, a trifluoromethyl group, a pyrazole group, and an ethyl formate group. It has a melting point of about 74-76°C and its solubility depends on the solvent, being soluble in organic solvents such as dimethyl sulfoxide and methylene chloride, and slightly soluble in ethanol and ether.

Use:
1-phenyl-3-(trifluoromethyl)-, ethyl ester is mainly used in organic synthesis reactions. It can be used as a pharmaceutical intermediate for the synthesis of biologically active compounds. For example, it has a wide range of applications in the field of pesticides and pharmaceuticals.

Preparation Method:
The synthesis of 1-phenyl-3-(trifluoromethyl)-, ethyl ester can be obtained by the reaction of phenylacetylene and trifluoromethylheptadienone under maloney nitrile reaction conditions. The specific synthetic route includes the steps of ketone oxidation, the reaction of pentadienone and phenylacetylene, and acid-catalyzed formation of pyrazole ring.

Safety Information:
1-phenyl-3-(trifluoromethyl)-, ethyl ester has limited toxicity information, but as an organic compound, care should be taken to prevent skin and eye contact. Adequate ventilation and appropriate protective equipment should be worn during use or handling. If irritation or allergic reactions occur, discontinue use immediately and seek medical help.

Last Update：2024-04-09 15:17:59