7268-43-1
5-oxopyrrolidine-3-carboxylic acid
CAS: 7268-43-1
Molecular Formula: C5H7NO3
7268-43-1 - Names and Identifiers
7268-43-1 - Physico-chemical Properties
| Molecular Formula | C5H7NO3 |
| Molar Mass | 129.11 |
| Density | 1.381g/cm3 |
| Boling Point | 453.134°C at 760 mmHg |
| Flash Point | 227.848°C |
| Vapor Presure | 0mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.512 |
7268-43-1 - Risk and Safety
| Hazard Class | IRRITANT |
7268-43-1 - Introduction
Acid is an organic compound with the chemical formula C5H7NO3. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: white crystal or crystalline powder;
-Melting point: 139-143°C;
-Solubility: Slightly soluble in water, soluble in acid and alkali solutions;
-Stability: Stable at room temperature and pressure.
Use:
Acid is an important intermediate in organic synthesis, mainly used to prepare other organic compounds and drugs. It is used in the field of medicine for the synthesis of potential antitumor and antiviral drugs, and also for the synthesis of other bioactive compounds and dyes.
Preparation Method:
The acid is generally synthesized by the following methods:
1. Pyrrolidine is mixed with nitric acid and nitrated under appropriate conditions to generate 5-nitropyrrolidine.
2. 5-aminopyrrolidine is obtained by reduction reaction of 5-nitropyrrolidine.
3. React 5-aminopyrrolidine with carbon dioxide, and carry out carboxylation reaction under appropriate conditions to generate acid.
Safety Information:
Acid has no obvious toxicity and danger under normal use conditions, but it still needs to be handled with caution. Avoid contact with skin and eyes during operation. If taken by mistake or inhaled, seek medical help immediately. At the same time, the storage should be sealed, away from the fire and oxidant.
Nature:
-Appearance: white crystal or crystalline powder;
-Melting point: 139-143°C;
-Solubility: Slightly soluble in water, soluble in acid and alkali solutions;
-Stability: Stable at room temperature and pressure.
Use:
Acid is an important intermediate in organic synthesis, mainly used to prepare other organic compounds and drugs. It is used in the field of medicine for the synthesis of potential antitumor and antiviral drugs, and also for the synthesis of other bioactive compounds and dyes.
Preparation Method:
The acid is generally synthesized by the following methods:
1. Pyrrolidine is mixed with nitric acid and nitrated under appropriate conditions to generate 5-nitropyrrolidine.
2. 5-aminopyrrolidine is obtained by reduction reaction of 5-nitropyrrolidine.
3. React 5-aminopyrrolidine with carbon dioxide, and carry out carboxylation reaction under appropriate conditions to generate acid.
Safety Information:
Acid has no obvious toxicity and danger under normal use conditions, but it still needs to be handled with caution. Avoid contact with skin and eyes during operation. If taken by mistake or inhaled, seek medical help immediately. At the same time, the storage should be sealed, away from the fire and oxidant.
Last Update：2024-04-09 21:11:58
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